RGS20 antibody (all Isoforms, Middle Region)

Catalog No. ABIN1108878

Product Details anti-RGS20 Antibody

Target: RGS20 (Regulator of G-Protein Signaling 20 (RGS20))

Binding Specificity: all Isoforms, Middle Region

Reactivity: Human, Mouse, Rat, Cow, Zebrafish (Danio rerio), Dog, Chicken, Xenopus laevis

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RGS20 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Sequence: NAFREFLRTE FSEENMLFWM ACEELKKEAN KNIIEEKARI IYEDYISILS

Specificity: This antibody wil detect all isoforms of RGS20.

Cross-Reactivity (Details): Species reactivity (expected):Mouse, Rat, Dog, Zebrafish, Bovine, African clawed frog, ChickenSpecies reactivity (tested):Human

Purification: Purified using Protein A affinity column

Immunogen: The immunogen for anti-RGS20 antibody: synthetic peptide directed towards the middle region of human RGS20

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Reconstitution: Add 100 μL of distilled water to a final concentration of 1 mg/mL.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store lyophilized at 2-8 °C or at -20 °C long term. After reconstitution store the antibody undiluted at 2-8 °C for up to one month or in aliquots at -20 °C long term.

Target Details for RGS20

Target: RGS20 (Regulator of G-Protein Signaling 20 (RGS20))

Alternative Name: RGS20 (RGS20 Products)

Background: Regulator of G protein signaling (RGS) proteins are regulatory and structural components of G protein-coupled receptor complexes. RGS proteins are GTPase-activating proteins for Gi and Gq class G-alpha proteins. They accelerate transit through the cycle of GTP binding and hydrolysis and thereby accelerate signaling kinetics and termination.Synonyms: Gz-GAP, RGSZ1, Regulator of G-protein signaling 20, Regulator of G-protein signaling Z1, Regulator of Gz-selective protein signaling 1, ZGAP1

Gene ID: 8601

NCBI Accession: NP_003693

Pathways: Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling