RGS20 antibody (AA 150-184)

Catalog No. ABIN6243829

Product Details anti-RGS20 Antibody

Target: RGS20 (Regulator of G-Protein Signaling 20 (RGS20))

Binding Specificity: AA 150-184

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RGS20 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This RGS20 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 150-184 amino acids from the Central region of human RGS20.

Clone: RB49337

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

Target Details for RGS20

Target: RGS20 (Regulator of G-Protein Signaling 20 (RGS20))

Alternative Name: RGS20 (RGS20 Products)

Synonyms: RGSZ1 antibody, ZGAP1 antibody, zgc:92650 antibody, rgsz1 antibody, zgap1 antibody, GzGAP antibody, RSG20 antibody, 2900073E09Rik antibody, Rgsz1 antibody, regulator of G protein signaling 20 antibody, regulator of G-protein signaling 20 L homeolog antibody, regulator of G-protein signaling 20 antibody, RGS20 antibody, rgs20 antibody, rgs20.L antibody, Rgs20 antibody

Background: Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds selectively to G(z)-alpha and G(alpha)-i2 subunits, accelerates their GTPase activity and regulates their signaling activities. The G(z)-alpha activity is inhibited by the phosphorylation and palmitoylation of the G- protein. Negatively regulates mu-opioid receptor-mediated activation of the G-proteins (By similarity).

Molecular Weight: 43692

UniProt: O76081

Pathways: Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling