IKAROS Family Zinc Finger 5 (Pegasus) (IKZF5) (N-Term) antibody

Details for Product No. ABIN1109610
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Antigen
Synonyms 2610034F18Rik, PEGASUS, Zfpn1a5, pegasus, znfn1a5, ZNFN1A5
Epitope
N-Term
(3), (1), (1), (1)
Reactivity
Xenopus laevis, Cow (Bovine), Dog (Canine), Chicken, Human, Mouse (Murine), Rat (Rattus), Zebrafish (Danio rerio)
(6), (2), (2), (2), (2), (2), (2), (1), (1)
Host
Rabbit
(4), (2)
Clonality
Polyclonal
Application
Immunohistochemistry (Frozen Paraffin-embedded Sections) (IHC (frpe)), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
(6), (3), (1), (1)
Pubmed 1 reference available
Quantity 50 μg
Shipping to United States (Change)
Availability Will be delivered in 6 to 8 Business Days
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Catalog No. ABIN1109610
401.50 $
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Immunogen The immunogen for anti-ZNFN1A5 antibody: synthetic peptide directed towards the N terminal of human ZNFN1A5
Sequence MGEKKPEPLD FVKDFQEYLT QQTHHVNMIS GSVSGDKEAE ALQGAGTDGD
Cross-Reactivity (Details) Species reactivity (expected):Mouse, Rat, Dog, Bovine, Chicken, Zebrafish, African clawed frogSpecies reactivity (tested):Human
Purification Purified using peptide immunoaffinity column
Alternative Name ZNFN1A5 / IKZF5 / Pegasus
Background IKZF5 also called ZNFN1A5 or Pegasus is a DNA-binding protein that binds to the 5'GNNTGTNG-3' core sequence and acts as transcriptional repressor. Interacts with other family members, IKZF1, IKZF2, IKZF3 AND IKZF4. Expressed in brain, heart, skeletal muscle, kidney, and liver. Expressed in the hematopoietic cell lines MOLT-4, NALM-6 and K-562. Highly expressed in THP-1 and M-07e cell lines, which have characteristics of myeloid and early megakaryocytic cells respectively.Synonyms: Ikaros family zinc finger protein 5, Zinc finger protein Pegasus
Gene ID 64376
NCBI Accession NP_071911
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Reconstitution Add 50 μL of distilled water to a final concentration of 1 mg/mL.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store lyophilized at 2-8 °C or at -20 °C long term. After reconstitution store the antibody undiluted at 2-8 °C for up to one month or in aliquots at -20 °C long term.
Background publications Perdomo, Holmes, Chong et al.: "Eos and pegasus, two members of the Ikaros family of proteins with distinct DNA binding activities." in: The Journal of biological chemistry, Vol. 275, Issue 49, pp. 38347-54, 2001 (PubMed).

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