EPO antibody
Quick Overview for EPO antibody (ABIN112537)
Target
See all EPO AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Specificity
- Reacts with an antigenic determinant in native and recombinant Human EPO. Does not react with other Human serum proteins.
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Purification
- Affinity Chromatography on Protein A
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Immunogen
- Recombinant EPO
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Isotype
- IgG1
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Application Notes
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ELISA (1/3,500,000 - 1/14,000,000).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- PBS, pH 7.2, containing 0.09 % Sodium Azide as preservative
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Preservative
- Sodium azide
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Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Dilute only prior to immediate use. Freezing alkaline phosphatase conjugates will result in a substantial loss of enzymatic activity.
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Storage
- 4 °C
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Storage Comment
- Store the antibody undiluted at 2-8 °C DO NOT FREEZE.
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- EPO (Erythropoietin (EPO))
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Alternative Name
- Erythropoietin / EPO
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Target Type
- Hormone
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Background
- Human Erythropoietin is member of the EPO/TPO family and encodes a secreted, glycosylated cytokine hormone composed of four alpha helical bundles. The protein is found in the plasma and regulates red cell production by promoting erythroid differentiation and initiating hemoglobin synthesis. This protein also has neuroprotective activity against a variety of potential brain injuries and antiapoptotic functions in several tissue types. It is produced by kidney or liver of adult mammals and by liver of fetal or neonatal mammals.Synonyms: Epoetin
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Gene ID
- 2056
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NCBI Accession
- NP_000790
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UniProt
- P01588
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Pathways
- JAK-STAT Signaling, Hormone Activity, Negative Regulation of intrinsic apoptotic Signaling, Negative Regulation of Transporter Activity
Target
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