IL1R2 antibody

Catalog No. ABIN112603

This Mouse Monoclonal antibody specifically detects IL1R2 in WB and EIA. It exhibits reactivity toward Human.

Quick Overview for IL1R2 antibody (ABIN112603)

Target: IL1R2 (Interleukin 1 Receptor, Type II (IL1R2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This IL1R2 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Clone: 49-20

Product Details anti-IL1R2 Antibody

Purification: Chromatography on Protein G

Immunogen: R-DNA. Human interleukin-1 soluble receptor, type 1 expressed in insect cell line Sf.

Isotype: IgG1

Application Details

Application Notes: ELISA. Western Blot.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: PBS buffer, pH 7.2 with 5 % trehalose

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: The antibody can be shipped at 2-8 °C. Store (in aliquots) at -20 °C only.

Target Details for IL1R2

Target: IL1R2 (Interleukin 1 Receptor, Type II (IL1R2))

Alternative Name: CD121b / IL1R2

Background: IL1 Receptor II is a cytokine receptor that belongs to the interleukin 1 receptor family. This protein binds interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I(IL1R1/IL1RA), and acts as a decoy receptor that inhibits the activity of its ligands. Interleukin 4 (IL4) is reported to antagonize the activity of interleukin 1 by inducing the expression and release of this cytokine. This gene and three other genes form a cytokine receptor gene cluster on chromosome 2q12. Two alternatively spliced transcript variants encoding the same protein have been reported.Synonyms: CD121 antigen-like family member B, CDw121b, IL-1R-2, IL-1R-beta, IL1RB, Interleukin-1 receptor type II

Gene ID: 9606

UniProt: P27930

Pathways: NF-kappaB Signaling