CTXB antibody
This Rabbit Polyclonal antibody specifically detects CTXB in EIA and IP. It exhibits reactivity toward Vibrio cholerae.
Catalog No. ABIN113086
$1,452.00
Plus shipping costs $50.00
1 mL
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United States
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Quick Overview for CTXB antibody (ABIN113086)
Target
CTXB
(CtxB Gene Product (CTXB))
Reactivity
Vibrio cholerae
Host
Rabbit
Clonality
Polyclonal
Conjugate
This CTXB antibody is un-conjugated
Application
Enzyme Immunoassay (EIA), Immunoprecipitation (IP)
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Specificity
- Beta subunit of Cholera toxin.
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Purification
- Protein A chromatography.
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Immunogen
- Purified choleragenoid.
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Application Notes
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ELISA: Titer: >1: 1,000. Also suitable for conjugation purposes. Immunoprecipitates toxin in gel techniques.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 4-5 mg/mL (OD280nm, E0.1% = 1.4)
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Buffer
- 0.01 M PBS, pH 7.2 with 0.09 % sodium azide as preservative.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freezing and thawing.
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Storage
- 4 °C/-20 °C
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Storage Comment
- Store the antibody at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- CTXB (CtxB Gene Product (CTXB))
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Alternative Name
- Cholera Enterotoxin Subunit B
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Background
- The B subunit of cholera toxin (CtxB) binds to a GM1-ganglioside receptor, a ubiquitous glycolipid cell surface receptor. This binding is widely accepted to initiate toxin action by triggering uptake and delivery of the toxin A subunit into cells. The beta chain has no toxic activity by itself. The holotoxin consists of a pentameric ring of B subunits whose central pore is occupied by the A subunit. The A subunit contains two chains, A1 and A2, linked by a disulfide bridge. The A subunit (and Cholera toxin) activates the adenylate cyclase enzyme in cells of the intestinal mucosa leading to increased levels of intracellular cAMP.Synonyms: Cholera enterotoxin B chain, Cholera enterotoxin gamma chain, Choleragenoid, VC_1456, ctxB, toxB
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Gene ID
- 2613962
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NCBI Accession
- NP_231099
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UniProt
- P01556
Target
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