CTXB antibody
CTXB
Reactivity: Vibrio cholerae
EIA, IHC (fro), IP, IF
Host: Rabbit
Polyclonal
unconjugated
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- Target See all CTXB products
- CTXB (CtxB Gene Product (CTXB))
- Reactivity
- Vibrio cholerae
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CTXB antibody is un-conjugated
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Application
- Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoprecipitation (IP), Immunofluorescence (IF)
- Specificity
- Reacts with the beta subunit of Cholera Toxin.
- Purification
- Ig Fraction
- Immunogen
- Purified choleragenoid
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- Application Notes
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ELISA. Immunoprecipitation. Has been described to work in Immunohistochemistry on Frozen Sections andImmunofluorescence.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1.0 mg/mL
- Buffer
- PBS, pH 7.2 containing 0.09 % Sodium Azide as preservative.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Target
- CTXB (CtxB Gene Product (CTXB))
- Alternative Name
- Cholera Enterotoxin Subunit B (CTXB Products)
- Background
- The beta subunit of cholera toxin binds to a GM1-anglioside receptor which is widely accepted to initiate toxin action by triggering uptake and delivery of the toxin alpha subunit into cells. The holotoxin consists of a pentameric ring of beta subunits whose central pore is occupied by the alpha subunit. The alpha subunit contains two chains, A1 and A2, linked by a disulfide bridge. The alpha subunit (and cholera toxin) activate the adenylate cyclase enzyme in cells of the intestinal mucosa leading to increased levels of intracellular cAMP.Synonyms: Cholera enterotoxin B chain, Cholera enterotoxin gamma chain, Choleragenoid, VC_1456, ctxB, toxB
- Gene ID
- 2613962
- NCBI Accession
- NP_231099
- UniProt
- P01556
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