CTXB antibody

Catalog No. ABIN112701

The Rabbit Polyclonal anti-CTXB antibody (ABIN112701) specifically detects CTXB in EIA, IHC (fro), IP and IF. The antibody is reactive with Vibrio cholerae samples.

Quick Overview for CTXB antibody (ABIN112701)

Target: CTXB (CtxB Gene Product (CTXB))

Reactivity: Vibrio cholerae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CTXB antibody is un-conjugated

Application: Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoprecipitation (IP), Immunofluorescence (IF)

Product Details anti-CTXB Antibody

Specificity: Reacts with the beta subunit of Cholera Toxin.

Purification: Ig Fraction

Immunogen: Purified choleragenoid

Application Details

Application Notes: ELISA. Immunoprecipitation. Has been described to work in Immunohistochemistry on Frozen Sections andImmunofluorescence.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: PBS, pH 7.2 containing 0.09 % Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for CTXB

Target: CTXB (CtxB Gene Product (CTXB))

Alternative Name: Cholera Enterotoxin Subunit B

Background: The beta subunit of cholera toxin binds to a GM1-anglioside receptor which is widely accepted to initiate toxin action by triggering uptake and delivery of the toxin alpha subunit into cells. The holotoxin consists of a pentameric ring of beta subunits whose central pore is occupied by the alpha subunit. The alpha subunit contains two chains, A1 and A2, linked by a disulfide bridge. The alpha subunit (and cholera toxin) activate the adenylate cyclase enzyme in cells of the intestinal mucosa leading to increased levels of intracellular cAMP.Synonyms: Cholera enterotoxin B chain, Cholera enterotoxin gamma chain, Choleragenoid, VC_1456, ctxB, toxB

Gene ID: 2613962

NCBI Accession: NP_231099

UniProt: P01556