G Protein alpha 0 (AA 345-354) antibody

Antigen: G Protein alpha 0

Epitope: AA 345-354

Clonality: Polyclonal

Host: Rabbit

Reactivity: Mouse (Murine)

Application: Western Blotting (WB)

Catalog no.: ABIN114078

Additional Information

Characteristics: Synonyms: Gnao1, Gna0, Gnao, Guanine nucleotide-binding protein G(o) subunit alpha

Alternative name: G protein alpha 0 (345-354)

Gene ID: 14681

Swiss-Prot: P18872

Immunogen: Synthetic peptide corresponding to the amino acids 345 - 354 of the native moleculeconjugated to Keyhole Limpet HaemocyaninAA Sequence: {C-}A-N-N-L-R-G-C-G-L-Y

Description: GTP binding proteins (G proteins) play a critical role in signal transduction by couplingreceptors to effectors. The intracellular consequences of G protein activation includesecond messenger generation, protein phosphorylation, ion channel activation, geneinduction, cell growth, and differentiation. Go belongs to the pertussis toxin sensitive Gproteins. It consists of two subtypes of a subunits (ao1 and ao2) derived from alternativesplicing of a single gene. ao1 differs from ao2 within the C terminal.

Specificity: This antibody detects G Protein-alpha 0. Species: Mouse. Others not tested.

Application Details

Application Notes: ELISA (1/100K - 1/400K). Western blot (gives a band at 39 kDa when used under reducing conditions against ratbrain). Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.

Concentration: 2.4 mg/ml (lot spec.)

Buffer: PBS , pH 7.2, 0.09 % Sodium Azide

Storage: Store the antibody at -20 °C. Can be shipped at 2 - 8 °C. Avoid repeated freezing and thawing. Shelf life: One year from despatch.

Restrictions: For Research Use only