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HLA-ABC antibody

The Mouse Monoclonal anti-HLA-ABC antibody (Clone LY5-1) (ABIN114528) specifically detects HLA-ABC in IHC (fro). The antibody is reactive with Human samples.
Catalog No. ABIN114528
$1,026.00
Plus shipping costs $50.00
0.5 mg
Shipping to: United States
Delivery in 1 to 2 Business Days

Quick Overview for HLA-ABC antibody (ABIN114528)

Target

See all HLA-ABC Antibodies
HLA-ABC

Reactivity

  • 91
  • 28
  • 19
  • 17
  • 15
  • 13
  • 13
  • 13
  • 12
  • 11
  • 7
  • 7
  • 6
  • 6
  • 2
  • 2
  • 1
Human

Host

  • 68
  • 18
  • 4
  • 1
Mouse

Clonality

  • 81
  • 9
Monoclonal

Conjugate

  • 45
  • 7
  • 7
  • 7
  • 5
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This HLA-ABC antibody is un-conjugated

Application

  • 65
  • 18
  • 17
  • 16
  • 16
  • 15
  • 10
  • 6
  • 4
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone

LY5-1
  • Purification

    Affinity Chromatography on Protein G.

    Immunogen

    Purified class I HLA complex.

    Isotype

    IgG1
  • Application Notes

    Immunohistochemistry on Frozen Sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Restrictions

    For Research Use only
  • Reconstitution

    Restore in Double distillated water

    Concentration

    1.0 mg/mL

    Buffer

    0.01 M PBS, pH 7.2

    Precaution of Use

    This product contains sodium azide : a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handling Advice

    This product is photosensitive and should be protected from light. Should this product contain a precipitate we recommend microcentrifugation before use. 12 months from date of reconstitution.

    Storage

    4 °C

    Storage Comment

    Prior to reconstitution store at +4 °C. Following reconstitution store at +4 °C. DO NOT FREEZE. This product should be stored undiluted.
  • Target

    HLA-ABC

    Alternative Name

    HLA Class I ABC

    Background

    Human leukocyte antigen (HLA) is the antigen binding, membrane bound α chain of major histocompatibility complex I (MHC1). While the small β chain is the invariable beta 2 microglobulin, the α chain has three major isoforms (HLA-A, HLA-B, HLA-C) that are encoding by different loci on chromosome 6 and each of the isoforms has a highly variable region that resembles Fab on immunoglobulin. The HLA-ABC antibody reacts with a common epitope shared by HLA-A, HLAB and HLA-C.Synonyms: HLA Class 2 ABC, Human Leukocyte antigen class I ABC, MHC class I ABC, Major Histocompatibility complex class I

    Pathways

    TCR Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
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