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HLA-ABC antibody

HLA-ABC Reactivity: Human, Mouse, Non-Human Primate FACS, IF Host: Mouse Monoclonal 246-B8-E7 unconjugated
Catalog No. ABIN6939617
  • Target See all HLA-ABC Antibodies
    HLA-ABC
    Reactivity
    • 69
    • 23
    • 14
    • 13
    • 12
    • 11
    • 10
    • 10
    • 8
    • 7
    • 7
    • 5
    • 1
    • 1
    • 1
    Human, Mouse, Non-Human Primate
    Host
    • 57
    • 9
    • 3
    Mouse
    Clonality
    • 59
    • 9
    Monoclonal
    Conjugate
    • 30
    • 8
    • 6
    • 6
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This HLA-ABC antibody is un-conjugated
    Application
    • 53
    • 18
    • 18
    • 10
    • 10
    • 10
    • 8
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunofluorescence (IF)
    Specificity
    Reacts with a monomorphic determinant of human major histocompatibility (MHC) class I antigens (HLA-A, B and C). Human MHC class I antigens are expressed constitutively on all nucleated cells lymphocytes such as lymphocytes, thymocytes, granulocytes, and bone marrow cells and are absent on erythrocytes. MHC class I antigens play a role in class I MHC-associated antigen presentation, inhibition of NK cell cytotoxicity, tumor surveillance, and tissue allotransplantation.
    Purification
    Purified by Protein A/G
    Immunogen
    Human peripheral blood leukocytes
    Clone
    246-B8-E7
    Isotype
    IgG2a kappa
    Top Product
    Discover our top product HLA-ABC Primary Antibody
  • Application Notes

    Positive Control: THP-1 and Jurkat cells. Tonsil or lymph node.

    Known Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Optimal dilution for a specific application should be determined.

    Restrictions
    For Research Use only
  • Concentration
    200 μg/mL
    Buffer
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-80 °C
    Storage Comment
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    Expiry Date
    24 months
  • Target
    HLA-ABC
    Alternative Name
    HLA-A, HLA-B, HLA-C (HLA-ABC Products)
    Synonyms
    HLAA antibody, major histocompatibility complex, class I, A antibody, HLA-A antibody
    Molecular Weight
    ~41kDa
    Gene ID
    3105, 3106, 3107
    UniProt
    P01889, P30443, P30499
    Pathways
    TCR Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
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