CSF3R antibody

Catalog No. ABIN114568

This Mouse Monoclonal antibody specifically detects CSF3R in WB and EIA. It exhibits reactivity toward Human.

Quick Overview for CSF3R antibody (ABIN114568)

Target: CSF3R (Colony Stimulating Factor 3 Receptor (Granulocyte) (CSF3R))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CSF3R antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Clone: S-425

Product Details anti-CSF3R Antibody

Specificity: Reactive with G-CSFR and does not cross-react with MBP or BSA (bovine serum albumin).

Purification: Protein G affinity purified

Immunogen: Purified recombinant MBP-GCSFR fusion protein

Isotype: IgG2a

Application Details

Application Notes: ELISA. Immunoblotting: Recognizes denatured G-CSFR following SDS-PAGE and blotting of 200 μgof cell lysate or following immunoprecipitation with polyclonal antibody followed byimmunoblotting. Western Blot: At an antibody concentration of 1-10 μg/mL will allow visualization of 250 ng/lane of human G-CSFR-MBP.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Reconstitution: Restore with double distillated water is recommended to adjust the final concentration to 1.00 mg/mL

Buffer: 0.01 M PBS, pH 7.2

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.

Target Details for CSF3R

Target: CSF3R (Colony Stimulating Factor 3 Receptor (Granulocyte) (CSF3R))

Alternative Name: CD114 / CSF3R

Background: The protein encoded by the GCSF Receptor gene is the receptor for colony stimulating factor 3, a cytokine that controls the production, differentiation, and function of granulocytes. The encoded protein, which is a member of the family of cytokine receptors, may also function in some cell surface adhesion or recognition processes. Four transcript variants encoding four different isoforms have been found for this gene, of which three are membrane-bound and the one secreted and soluble. Mutations in this gene are a cause of Kostmann syndrome, also known as severe congenital neutropenia.Synonyms: G-CSF Receptor, G-CSF-R, GCSF Receptor, GCSFR, Granulocyte colony-stimulating factor receptor

Gene ID: 1441

NCBI Accession: NP_000751

UniProt: Q99062