Chemokine (C-C Motif) Ligand 7 (CCL7) antibody
| Antigen |
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| Synonyms |
FIC, MARC, MCP3, NC28, MCP-3, SCYA6, SCYA7, MGC138463, MGC138465, CCL7 |
| Clonality |
Monoclonal (113) |
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Host
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Reactivity
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Conjugate
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Biotin (16), HRP (4), FITC (3), Alexa Fluor 350 (2), Alexa Fluor 488 (2), Alexa Fluor 555 (2), Alexa Fluor 647 (2), Cy3 (2), Cy5 (2), Cy5.5 (2), Cy7 (2), Gold (2), PE (2), PE,Cy3 (2), PE,Cy5 (2), PE,Cy5.5 (2), PE,Cy7 (2)
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Application
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ELISA (80), Western Blotting (WB) (74), Immunofluorescence (IF) (30), Functional Studies (Func) (10), Immunohistochemistry (IHC) (9), Neutralization (Neut) (8), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (6), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (6), Immunoprecipitation (IP) (5), Blocking Antibody (Inhibition) (3), Blocking Antibody (Inhibition) (2), Immunoelectron Microscopy (IEM) (2), Transfected cell culture (TCC) (2)
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| Catalog no. |
ABIN114715 |
| Quantity |
0.5 mg |
| Price |
451.00 $ Plus shipping costs $45.00
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| Shipping to |
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| Availability |
Will be delivered in 6 to 8 Business Days |
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Alternative name
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MCP3 / CCL7
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UniProt
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P80098
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Immunogen
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Recombinant human MCP-3 (M. W. 8. 5 kDa containing 76 amino acids residues).
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Cross-Reactivity
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Human
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Isotype
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IgG1
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Clone
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113
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Description
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MCP3/CCL7 is a secreted chemokine which attracts macrophages during inflammation andmetastasis. It is a member of the C-C subfamily of chemokines which are characterized byhaving two adjacent cysteine residues. The protein is an in vivo substrate of matrixmetalloproteinase 2, an enzyme which degrades components of the extracellular matrix.
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Characteristics
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Synonyms: Small-inducible cytokine A7, CCL-7, MCP-3, C-C motif chemokine 7, SCYA6, SCYA7, NC28,Macrophage Chemotactic Protein-3, Monocyte chemoattractant protein 3, Monocytechemotactic protein 3
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Application Notes
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ELISA. Western Blot: CCL7 antibody concentration of 1-4 µg/mL will allow visualization of 0.1µg/lane of human MCP-3. Matched Pair: DM2035 Clone 113DM2039 Clone 542Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
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Purification
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Purified
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Buffer
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0.01M PBS, pH 7.2 without preservatives.Reconstitution: Restore with double distillated water to adjust the final concentration to1.00 mg/ml
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Storage
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Store the antibody at -20°C. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
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Research Area
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Cytokines, Chemokines
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Restrictions
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For Research Use only
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Houmand, Abrahamsen, Tinggaard Pedersen: "Relevance of Ki-67 expression in the classification of non-Hodgkin's lymphomas: a morphometric and double-immunostaining study." in: Histopathology, Vol. 20, Issue 1, pp. 13-20, 1992 (PubMed).
Gerdes, Schwab, Lemke et al.: "Production of a mouse monoclonal antibody reactive with a human nuclear antigen associated with cell proliferation." in: International journal of cancer. Journal international du cancer, Vol. 31, Issue 1, pp. 13-20, 1983 (PubMed).
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Alternatives for antigen "Chemokine (C-C Motif) Ligand 7 (CCL7)", type "Antibodies"
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Hosts
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Rabbit (57), Mouse (36), Goat (22)
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Reactivities
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Human (81), Mouse (Murine) (33), Rat (Rattus) (18)
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Applications
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ELISA (80), Western Blotting (WB) (74), Immunofluorescence (IF) (30), Functional Studies (Func) (10), Immunohistochemistry (IHC) (9), Neutralization (Neut) (8), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (6), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (6), Immunoprecipitation (IP) (5), Blocking Antibody (Inhibition) (3), Blocking Antibody (Inhibition) (2), Immunoelectron Microscopy (IEM) (2), Transfected cell culture (TCC) (2)
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Conjugates
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Biotin (16), HRP (4), FITC (3), Alexa Fluor 350 (2), Alexa Fluor 488 (2), Alexa Fluor 555 (2), Alexa Fluor 647 (2), Cy3 (2), Cy5 (2), Cy5.5 (2), Cy7 (2), Gold (2), PE (2), PE,Cy3 (2), PE,Cy5 (2), PE,Cy5.5 (2), PE,Cy7 (2)
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Epitopes
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N-Term (1)
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Alternatives 
2013 BioMed Central Research Awards
