Chemokine (C-C Motif) Ligand 7 (CCL7) antibody

Details for Product No. ABIN114715
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Antigen
Synonyms CCL7, FIC, MARC, MCP-3, MCP3, NC28, SCYA6, SCYA7, Scya7, fic, marc, mcp3
Reactivity
Human
(102), (27), (12)
Host
Mouse
(59), (51), (15), (1), (1)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(13), (6), (5), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1)
Application
ELISA, Western Blotting (WB)
(90), (90), (20), (10), (10), (9), (7), (5), (5), (4), (3), (2), (2)
Pubmed 2 references available
Quantity 0.5 mg
Shipping to United States (Change)
Availability Will be delivered in 6 to 8 Business Days
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Catalog No. ABIN114715
489.50 $
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Immunogen Recombinant human MCP-3 (M.W. 8.5 kDa containing 76 amino acids residues).
Clone 5H9
Isotype IgG1
Specificity Reactive with natural and recombinant human MCP-3. Does not show any cross reaction with other Human Cytokines or growth factors tested such as IL1 beta, IL-8, MCAF, SAA and EGF.
Purification Affinity Chromatography on Protein G.
Alternative Name MCP3 / CCL7
Background MCP3/CCL7 is a secreted chemokine which attracts macrophages during inflammation and metastasis. It is a member of the C-C subfamily of chemokines which are characterized by having two adjacent cysteine residues. The protein is an in vivo substrate of matrix metalloproteinase 2, an enzyme which degrades components of the extracellular matrix.
Alternate names: C-C motif chemokine 7, CCL-7, MCP-3, Macrophage Chemotactic Protein-3, Monocyte chemoattractant protein 3, Monocyte chemotactic protein 3, NC28, SCYA6, SCYA7, Small- inducible cytokine A7
Gene ID 6354
NCBI Accession NP_006264
UniProt P80098
Research Area Cytokines, Chemokines
Application Notes ELISA. Western Blot: CCL7 antibody concentration of 1-4 µg/mL will allow visualization of 0.1µg/lane of human MCP-3. Matched Pair: DM2035 Clone 113DM2039 Clone 542Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Restore with double distillated water to adjust the final concentration to 1.00 mg/mL
Buffer 0.01M PBS, pH 7.2 without preservatives.
Preservative Without preservative
Handling Advice This product is photosensitive and should be protected from light
Storage 4 °C
Storage Comment Store the antibody at 2 - 8 °C. DO NOT FREEZE! If the reagent is being diluted, it is recommended that only the quantity to be used withing one week be diluted.
Expiry Date 12 months
General Houmand, Abrahamsen, Tinggaard Pedersen: "Relevance of Ki-67 expression in the classification of non-Hodgkin's lymphomas: a morphometric and double-immunostaining study." in: Histopathology, Vol. 20, Issue 1, pp. 13-20, 1992 (PubMed).

Gerdes, Schwab, Lemke et al.: "Production of a mouse monoclonal antibody reactive with a human nuclear antigen associated with cell proliferation." in: International journal of cancer. Journal international du cancer, Vol. 31, Issue 1, pp. 13-20, 1983 (PubMed).

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