CCL7 antibody (N-Term)

Catalog No. ABIN2777167

This Rabbit Polyclonal antibody specifically detects CCL7 in WB and IHC. It exhibits reactivity toward Human, Horse and Pig.

Quick Overview for CCL7 antibody (N-Term) (ABIN2777167)

Target: CCL7 (Chemokine (C-C Motif) Ligand 7 (CCL7))

Reactivity: Human, Horse, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCL7 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-CCL7 Antibody

Binding Specificity: N-Term

Purpose: CCL7 Antibody - N-terminal region

Sequence: TSTTCCYRFI NKKIPKQRLE SYRRTTSSHC PREAVIFKTK LDKEICADPT

Predicted Reactivity: Horse: 85%, Human: 100%, Pig: 100%

Characteristics: This is a rabbit polyclonal antibody against CCL7. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP30804-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for CCL7

Target: CCL7 (Chemokine (C-C Motif) Ligand 7 (CCL7))

Alternative Name: CCL7

Background:

Background Information: CCL7 encodes monocyte chemotactic protein 3, a secreted chemokine which attracts macrophages during inflammation and metastasis. It is a member of the C-C subfamily of chemokines which are characterized by having two adjacent cysteine residues. The protein is an in vivo substrate of matrix metalloproteinase 2, an enzyme which degrades components of the extracellular matrix. This gene is part of a cluster of C-C chemokine family members on chromosome 17q.

Gene Name: Chemokine (C-C motif) ligand 7

Alternative Symbols: FIC, MARC, MCP3, NC28, MCP-3, SCYA6, SCYA7

Protein Name: C-C motif chemokine 7

Molecular Weight: 11 kDa

Gene ID: 6354

NCBI Accession: NP_006264

UniProt: P80098