S100A/B (S100A/B) antibody

Antigen: S100A/B (S100A/B)

Clonality: Polyclonal

Host: Rabbit

Reactivity: Cow (Bovine), Human

Application: Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Catalog no.: ABIN115345

Additional Information

Characteristics: Synonyms: Protein S100-B, S100 beta, S100 calcium-binding protein B, S-100 protein subunit beta,S-100 protein beta chain, Astrocyte Marker

Alternative name: S100B (S100A/B)

Gene ID: 525716

Swiss-Prot: P02638

Immunogen: Affinity purified S-100 protein isolated from cow brain.

Description: The Antibody shows strong cross-reactivity with human S-100 A and B. In the brain, itlabels glial and ependymal cells. Melanocytes and Langerhans cells of the skin stainpositive with this antibody.

Specificity: This antibody reacts with cow S-100 protein A and B. Cellular Localization: CytoplasmicSpecies: Human. Others not tested.

Application Details

Application Notes: Immunohistochemistry on formalin-fixed paraffin embedded sections: diluted of 1: 50-1: 200 in an ABC method (30 minutes at room temperature)Recommended Positive Control: MelanomaOther applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.

Buffer: containing sodium azide as preservative.

Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Restrictions: For Research Use only

Publications

Publications: Winek, Scheithauer, Wick: "Meningioma, meningeal hemangiopericytoma (angioblastic meningioma), peripheral hemangiopericytoma, and acoustic schwannoma. A comparative immunohistochemical study." in: The American journal of surgical pathology, Vol. 13, Issue 4, pp. 251-61, 1989 (PubMed).

Kindblom, Lodding, Rosengren et al.: "S-100 protein in melanocytic tumors. An immunohistochemical investigation of benign and malignant melanocytic tumors and metastases of malignant melanoma and a characterization of the antigen in comparison to human brain." in: Acta pathologica, microbiologica, et immunologica Scandinavica. Section A, Pathology, Vol. 92, Issue 4, pp. 219-30, 1984 (PubMed).