SERPINA3 antibody

Catalog No. ABIN115360

This Rabbit Polyclonal antibody specifically detects SERPINA3 in IHC (p) and IHC (fro). It exhibits reactivity toward Human.

Quick Overview for SERPINA3 antibody (ABIN115360)

Target: SERPINA3 (serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 3 (SERPINA3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SERPINA3 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-SERPINA3 Antibody

Specificity: The antibody is specific against human alpha-1-antichymotrypsin.
Cellular Localization: Cytoplasmic.

Purification: Purified

Immunogen: Alpha-1-antichymotrypsin isolated from human serum

Application Details

Application Notes: Immunohistochemistry on frozen sections. Immunohistochemistry on formalin-fixed paraffin embedded sections: diluted of 1: 25-1: 50in an ABC method (30 minutes at room temperature). Recommended Positive Control: Tonsil.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Containing sodium azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for SERPINA3

Target: SERPINA3 (serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 3 (SERPINA3))

Alternative Name: alpha-1-Antichymotrypsin (ACT)

Background: Alpha 1 Antichymotrypsin is a plasma protease inhibitor and member of the serine protease inhibitor class. Polymorphisms in this protein appear to be tissue specific and influence protease targeting. Variation in this protein's sequence have been implicated in Alzheimer's disease, and deficiency of this protein has been associated with liver disease. Mutations have been identified in patients with Parkinson disease and chronic obstructive pulmonary disease.Synonyms: AACT, Cell growth-inhibiting gene 24/25 protein, GIG24, GIG25, SERPINA3

Gene ID: 12, 9606

UniProt: P01011