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ITGB1 antibody

ITGB1 Reactivity: Mouse, Rat FACS, IP, BR Host: Armenian Hamster Monoclonal Ha2-5 unconjugated
Catalog No. ABIN1177274
  • Target See all ITGB1 Antibodies
    ITGB1 (Integrin beta 1 (ITGB1))
    Reactivity
    • 208
    • 92
    • 76
    • 21
    • 18
    • 18
    • 17
    • 10
    • 8
    • 8
    • 7
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Mouse, Rat
    Host
    • 150
    • 70
    • 13
    • 6
    • 4
    • 1
    Armenian Hamster
    Clonality
    • 139
    • 101
    • 1
    Monoclonal
    Conjugate
    • 109
    • 22
    • 21
    • 14
    • 9
    • 6
    • 6
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This ITGB1 antibody is un-conjugated
    Application
    • 118
    • 115
    • 71
    • 55
    • 33
    • 27
    • 27
    • 26
    • 26
    • 18
    • 12
    • 7
    • 5
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunoprecipitation (IP), Blocking Reagent (BR)
    Brand
    BD Pharmingen™
    Purification
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    Sterility
    0.2 μm filtered
    Endotoxin Level
    Endotoxin level is ≤ 0.01 EU/μg (≤ 0.001 ng/μg) of protein as determined by the LAL assay.
    Immunogen
    Rat glomerular epithelial cells
    Clone
    Ha2-5
    Isotype
    IgM kappa
    Top Product
    Discover our top product ITGB1 Primary Antibody
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1.0 mg/mL
    Buffer
    No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered.
    Preservative
    Azide free
    Storage
    4 °C
    Storage Comment
    Store undiluted at 4°C. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
  • Mendrick, Kelly: "Temporal expression of VLA-2 and modulation of its ligand specificity by rat glomerular epithelial cells in vitro." in: Laboratory investigation; a journal of technical methods and pathology, Vol. 69, Issue 6, pp. 690-702, (1994) (PubMed).

    Springer: "Adhesion receptors of the immune system." in: Nature, Vol. 346, Issue 6283, pp. 425-34, (1990) (PubMed).

  • Target
    ITGB1 (Integrin beta 1 (ITGB1))
    Alternative Name
    CD29 (ITGB1 Products)
    Background
    The Ha2/5 antibody reacts with the 130 kDa integrin beta1 chain (CD29). CD29 is expressed on the cell surface as a heterodimer with one of the distinct integrin alpha chains. With alpha1 through alpha6 (CD49a through CD49f), it forms the VLA-1 through VLA-6 complexes, respectively, and with alphaV (CD51), it forms alphaVbeta1 integrin. As a result, CD29 has a broad tissue distribution, including lymphocytes, endothelia, smooth muscle, and epithelia. The Ha2/5 hamster anti-rat CD29 monoclonal antibody cross-reacts with mouse thymocytes, splenocytes, and peripheral lymph node leukocytes. The Ha2/5 antibody blocks in vitro adhesion of CD29-expressing cells to collagen.
    Synonyms: Integrin beta1 chain
    Pathways
    Cell-Cell Junction Organization, Regulation of G-Protein Coupled Receptor Protein Signaling, CXCR4-mediated Signaling Events, Signaling of Hepatocyte Growth Factor Receptor, Integrin Complex, SARS-CoV-2 Protein Interactome
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