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Integrin beta 2 (ITGB2) antibody

Antigen

Integrin beta 2 (ITGB2)

Synonyms 2E6, LAD, Cd18, Lfa1, MF17, LCAMB, AI528527, CD18, MFI7, LFA-1, MAC-1, CD61, GP3A, GPIIIa, INGRB3, MGC159221, MGC159223, ITGB2, integrin, ITGB3, MGC116306
Clonality Monoclonal (C71-16)
Host
Reactivity
Alternatives

Mouse (Murine)

Conjugate
Alternatives Un-conjugated
Application
Alternatives Immunohistochemistry (Frozen Sections) (IHC (fro)), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
5 references available
Catalog no. ABIN118151
Quantity 0.2 mg  (0.2 mg/ml)
Price 429.00 $   Plus shipping costs $45.00
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Availability Will be delivered in 6 to 8 Business Days

Additional Information

Alternative name CD18 / ITGB2
UniProt P11835
Immunogen Cell membrane glycoproteins derived from BW5147 cells (1)
Cross-Reactivity Mouse (Murine)
Isotype IgG2a
Clone C71-16

Application Details

Application Notes IHC on acetone-fixed frozen sections. Immunoprecipitation. Flow cytometry (please see protocol for details). Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Concentration 0.2 mg/ml
Purification Purified
Buffer PBS and 0.02% sodium azide (NaN3)
Storage Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing. Shelf Life: one year from despatch.
Research Area CD Antigens, Surface Receptors of Immune Cells
Restrictions For Research Use only

Publications

Springer: "Adhesion receptors of the immune system." in: Nature, Vol. 346, Issue 6283, pp. 425-34, 1990 (PubMed).

Larson, Springer: "Structure and function of leukocyte integrins." in: Immunological reviews, Vol. 114, pp. 181-217, 1990 (PubMed).

Springer, Davignon, Ho et al.: "LFA-1 and Lyt-2,3, molecules associated with T lymphocyte-mediated killing; and Mac-1, an LFA-1 homologue associated with complement receptor function." in: Immunological reviews, Vol. 68, pp. 171-95, 1983 (PubMed).

Trowbridge, Omary: "Molecular complexity of leukocyte surface glycoproteins related to the macrophage differentiation antigen Mac-1." in: The Journal of experimental medicine, Vol. 154, Issue 5, pp. 1517-24, 1982 (PubMed).

Springer: "Traffic signals for lymphocyte recirculation and leukocyte emigration: the multistep paradigm." in: Cell, Vol. 76, Issue 2, pp. 301-14, 1994 (PubMed).

Alternatives

Alternatives for antigen "Integrin beta 2 (ITGB2)", type "Antibodies"
Hosts Mouse (81), Rat (53), Rabbit (25), Goat (1), Hamster (1)
Reactivities Human (95), Mouse (Murine) (63), Rat (Rattus) (37), Pig (Porcine) (23), Cow (Bovine) (20), Horse (Equine) (18), Sheep (Ovine) (18), Dog (Canine) (13), Rabbit (1)
Applications Flow Cytometry (FACS) (126), Immunoprecipitation (IP) (56), Western Blotting (WB) (38), Functional Studies (Func) (24), Immunofluorescence (IF) (21), Immunohistochemistry (Fixed) (IHC (fx)) (14), Immunohistochemistry (Frozen Sections) (IHC (fro)) (14), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (13), ELISA (10), Immunohistochemistry (IHC) (6), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (3), Immunocytochemistry (ICC) (2), Blocking Antibody (Inhibition) (1), Immunoelectron Microscopy (IEM) (1)
Conjugates FITC (29), Biotin (19), PE (16), RPE (5), APC (4), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), Gold (1), HRP (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1)
Epitopes AA 534-546 (4), Activation Site (3), C-Term (1), N-Term (1), pThr758 (1)