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Integrin beta 2 antibody (AA 70-170)

ITGB2 Reactivity: Human WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN3023118
  • Target See all Integrin beta 2 (ITGB2) Antibodies
    Integrin beta 2 (ITGB2)
    Binding Specificity
    • 19
    • 15
    • 11
    • 8
    • 8
    • 6
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 70-170
    Reactivity
    • 191
    • 46
    • 45
    • 6
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 100
    • 92
    • 27
    • 2
    Rabbit
    Clonality
    • 124
    • 92
    • 2
    Polyclonal
    Conjugate
    • 89
    • 24
    • 20
    • 19
    • 10
    • 6
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Integrin beta 2 antibody is un-conjugated
    Application
    • 121
    • 84
    • 49
    • 48
    • 36
    • 30
    • 26
    • 26
    • 26
    • 26
    • 21
    • 13
    • 9
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequence
    MRGCAADDIM DPTSLAETQE DHNGGQKQLS PQKVTLYLRP GQAAAFNVTF RRAKGYPIDL YYLMDLSYSM LDDLRNVKKL GGDLLRALNE ITESGRIGFG S
    Cross-Reactivity
    Human, Mouse, Rat
    Characteristics
    Polyclonal Antibodies
    Immunogen
    A synthetic peptide corresponding to a sequence within amino acids 70-170 of human CD18 (NP_000202.3).
    Isotype
    IgG
    Top Product
    Discover our top product ITGB2 Primary Antibody
  • Application Notes
    WB,1:500 - 1:2000,IHC,1:50 - 1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid freeze / thaw cycles
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    Integrin beta 2 (ITGB2)
    Alternative Name
    ITGB2 (ITGB2 Products)
    Synonyms
    CD18 antibody, LAD antibody, LCAMB antibody, LFA-1 antibody, MAC-1 antibody, MF17 antibody, MFI7 antibody, 2E6 antibody, AI528527 antibody, Cd18 antibody, Lfa1 antibody, ITGB2 antibody, itgb2 antibody, itgb2-a antibody, itgb2-b antibody, integrin subunit beta 2 antibody, integrin beta 2 antibody, integrin subunit beta 2 S homeolog antibody, ITGB2 antibody, Itgb2 antibody, itgb2.S antibody
    Background
    This gene encodes an integrin beta chain, which combines with multiple different alpha chains to form different integrin heterodimers. Integrins are integral cell-surface proteins that participate in cell adhesion as well as cell-surface mediated signalling. The encoded protein plays an important role in immune response and defects in this gene cause leukocyte adhesion deficiency. Alternative splicing results in multiple transcript variants.,CD18,LAD,LCAMB,LFA-1,MAC-1,MF17,MFI7,ITGB2,Signal Transduction,G protein signaling,G2/M DNA Damage Checkpoint,PI3K-Akt Signaling Pathway,MAPK-Erk Signaling Pathway,Cell Biology & Developmental Biology,Cell Adhesion,Cytoskeleton,Immunology & Inflammation,CD markers,T Cell Receptor Signaling Pathway,Stem Cells,Hematopoietic Progenitors,ITGB2
    Molecular Weight
    84 kDa
    Gene ID
    3689
    UniProt
    P05107
    Pathways
    NF-kappaB Signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation
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