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Integrin beta 2 Products

(Integrin beta 2 (ITGB2))

Categories

The product of this gene belongs to the integrin beta chain family of proteins. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. This gene encodes the integrin beta chain beta 2. A given chain may combine with multiple partners resulting in different integrins. For example, beta 2 combines with the alpha L chain to form the integrin LFA-1, and combines with the alpha M chain to form the integrin Mac-1. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. Defects in this gene are the cause of leukocyte adhesion deficiency type I (LAD1). Two transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jul 2008].

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Featured Integrin beta 2 Categories

Integrin beta 2 Antibodies

High quality antibodies with extensive validation data.

Integrin beta 2 ELISA Kits

Reliable ELISA kits for a wide range of species.

Integrin beta 2 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Integrin beta 2 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application FACS, WB, IP, IHC (fro), IHC (p)
Validations
  • (5)
  • (6)
Cat. No. ABIN94005
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human
Application FACS, WB, IP, Func, IHC (fro), IHC (p)
Validations
  • (5)
  • (6)
Cat. No. ABIN2749019
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human
Application FACS, WB, IP, IHC (fro), IHC (p)
Validations
  • (5)
  • (5)
Cat. No. ABIN94007
Quantity 0.1 mg
Datasheet Datasheet

Recommended Integrin beta 2 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (5)
Cat. No. ABIN6574283
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6967700
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6967699
Quantity 96 tests
Datasheet Datasheet

Recommended Integrin beta 2 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1308201
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1308205
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3093240
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our Integrin beta 2 products

Blatchley, Hall, Wang, Pruitt, Gerecht: "Hypoxia and matrix viscoelasticity sequentially regulate endothelial progenitor cluster-based vasculogenesis." in: Science advances, Vol. 5, Issue 3, pp. eaau7518, (2019) (PubMed).

Ristow, Tran, Schwartz, Pankratz, Mehle, Sauer, Welch: "The Extracellular Domain of the β2 Integrin β Subunit (CD18) Is Sufficient for Escherichia coli Hemolysin and Aggregatibacter actinomycetemcomitans Leukotoxin Cytotoxic Activity." in: mBio, Vol. 10, Issue 4, (2019) (PubMed).

Yang, Jiang, Chen, He, Hu: "Protective effects of sinomenine against LPS-induced inflammation in piglets." in: Microbial pathogenesis, Vol. 110, pp. 573-577, (2018) (PubMed).

Lavoie, Dumas, Vulesevic, Neagoe, White, Sirois: "Synthesis of Human Neutrophil Extracellular Traps Contributes to Angiopoietin-Mediated In Vitro Proinflammatory and Proangiogenic Activities." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 200, Issue 11, pp. 3801-3813, (2018) (PubMed).

Benson, Li, Myers, Dorand, Gurkan, Huang, Ransohoff: "Biomimetic post-capillary venule expansions for leukocyte adhesion studies." in: Scientific reports, Vol. 8, Issue 1, pp. 9328, (2018) (PubMed).

Sheriff, Alanazi, Ward, Ward, Munir, Rayes, Alassiri, Watson, Newsome, Rainger, Kalia, Frampton, McGettrick, Nash: "Origin-Specific Adhesive Interactions of Mesenchymal Stem Cells with Platelets Influence Their Behavior After Infusion." in: Stem cells (Dayton, Ohio), Vol. 36, Issue 7, pp. 1062-1074, (2018) (PubMed).

Zhou, Zhao, Schwarz, Mangeat, Schwarz, Hamed, Bogeski, Helms, Rieger, Qu: "Bystander cells enhance NK cytotoxic efficiency by reducing search time." in: Scientific reports, Vol. 7, pp. 44357, (2017) (PubMed).

Eppler, Quast, Kolanus: "Dynamin2 controls Rap1 activation and integrin clustering in human T lymphocyte adhesion." in: PLoS ONE, Vol. 12, Issue 3, pp. e0172443, (2017) (PubMed).

Qi, Wei, Zhou, Yang, Li, Guo, Li, Ye, Li, Zhang, Lan, He, Cao, Zhou, Geng, Wang: "P-selectin-mediated platelet adhesion promotes tumor growth." in: Oncotarget, Vol. 6, Issue 9, pp. 6584-96, (2015) (PubMed).

Chenna Narendra, Chalise, Magnusson, Uppugunduri: "Local but Not Systemic Administration of Uridine Prevents Development of Antigen-Induced Arthritis." in: PLoS ONE, Vol. 10, Issue 10, pp. e0141863, (2015) (PubMed).

Synonyms and alternative names related to Integrin beta 2

integrin subunit beta 2 (ITGB2), integrin beta 2 (Itgb2), integrin subunit beta 2 (Itgb2), integrin subunit beta 2 S homeolog (itgb2.S), 2E6, AI528527, CD18, Cd18, ITGB2, itgb2, itgb2-a, itgb2-b, LAD, LCAMB, LFA-1, Lfa1, MAC-1, MF17, MFI7

Protein level used designations for Integrin beta 2

  • cell surface adhesion glycoprotein LFA-1/CR3/P150,959 beta subunit precursor)
  • cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta
  • complement receptor C3 beta-subunit
  • complement receptor C3 subunit beta
  • integrin beta chain, beta 2
  • integrin beta-2
  • leukocyte cell adhesion molecule CD18
  • leukocyte-associated antigens CD18/11A, CD18/11B, CD18/11C
  • Mac-1 beta
  • lymphocyte function associated antigen 1
  • macrophage antigen-1 beta
  • CD18 subunit
  • Leu-CAM receptor
  • integrin, beta 2 (antigen CD18 subunit (p95), lymphocyte function-associated antigen 1, integrin B2)
  • integrin beta 2 subunit
  • CD18 leukocyte adhesion molecule
  • antigen CD18
  • integrin beta-2 chain
  • integrin beta 2
  • integrin, beta 2 (antigen CD18 (p95), lymphocyte function-associated antigen 1
  • integrin, beta 2 (antigen CD18 (p95), lymphocyte function-associated antigen 1; macrophage antigen 1 (mac-1) beta subunit)
  • macrophage antigen 1 (mac-1) beta subunit)
  • Cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta
  • Complement receptor C3 subunit beta
  • Integrin beta-2
  • integrin beta-2 subunit
  • integrin subunit beta 2 S homeolog
  • integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
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