anti-Synaptophysin antibody (SYP)

Details for Product anti-SYP Antibody No. ABIN119030
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Antigen
Synonyms syp-B, xsypii, MGC86267, MRXSYP, A230093K24Rik, AI848995, Syn, p38, Syp1, mrxsyp, syp, xsypi
Reactivity
Hamster, Human, Pig (Porcine), Rat (Rattus)
(262), (83), (60), (30), (3), (2), (2), (2), (1), (1), (1), (1)
Host
Mouse
(187), (129), (6), (1)
Clonality (Clone)
Monoclonal ()
Conjugate
This Synaptophysin antibody is un-conjugated
(7), (5), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1)
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(235), (124), (88), (52), (42), (39), (17), (13), (11), (4), (4), (3), (2), (1)
Pubmed 9 references available
Quantity 0.2 mg
Shipping to United States ( )
Availability Will be delivered in 6 to 8 Business Days
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Immunogen Crude human synaptophysin immunoprecipitate. Spleen cells from immunised BALB/c mice were fused with cells of the NSO mouse myeloma cell line.
Clone SP15
Isotype IgM
Specificity This antibody recognises an antigen which appears to be identical to the synaptic vesicle protein synaptophysin. It reacts with synaptophysin expressed in CHO cells (3., 8.).
Purification Gel filtration.
Alternative Name Synaptophysin / SYP (SYP Antibody Abstract)
Background Synonyms: Major synaptic vesicle protein p38, Neuroendocrine Marker
Gene ID 6855
NCBI Accession NP_003170
UniProt P08247
Application Notes ELISA. Western Blot: 1/500. Immunohistochemistry on Paraffin Sections: 1/25. Recommended Positive Control: Pancreas.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Concentration 1.0 mg/mL
Buffer PBS, pH 7.2 containing 0.09 % Sodium Azide as preservative.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Background publications Honer, Beach, Hu et al.: "Hippocampal synaptic pathology in patients with temporal lobe epilepsy." in: Acta neuropathologica, Vol. 87, Issue 2, pp. 202-10, 1994 (PubMed).

Honer, Dickson, Gleeson et al.: "Regional synaptic pathology in Alzheimer's disease." in: Neurobiology of aging, Vol. 13, Issue 3, pp. 375-82, 1992 (PubMed).

General Simpson, Chundu, Davies-Hill et al.: "Decreased concentrations of GLUT1 and GLUT3 glucose transporters in the brains of patients with Alzheimer's disease." in: Annals of neurology, Vol. 35, Issue 5, pp. 546-51, 1994 (PubMed).

Masliah, Honer, Mallory et al.: "Topographical distribution of synaptic-associated proteins in the neuritic plaques of Alzheimer's disease hippocampus." in: Acta neuropathologica, Vol. 87, Issue 2, pp. 135-42, 1994 (PubMed).

Wakabayashi, Honer, Masliah: "Synapse alterations in the hippocampal-entorhinal formation in Alzheimer's disease with and without Lewy body disease." in: Brain research, Vol. 667, Issue 1, pp. 24-32, 1995 (PubMed).

Dickson, Davies, Bevona et al.: "Hippocampal sclerosis: a common pathological feature of dementia in very old (> or = 80 years of age) humans." in: Acta neuropathologica, Vol. 88, Issue 3, pp. 212-21, 1995 (PubMed).

Honer, Hu, Davies: "Human synaptic proteins with a heterogeneous distribution in cerebellum and visual cortex." in: Brain research, Vol. 609, Issue 1-2, pp. 9-20, 1993 (PubMed).

Honer, Kaufmann, Kleinman et al.: "Monoclonal antibodies to study the brain in schizophrenia." in: Brain research, Vol. 500, Issue 1-2, pp. 379-83, 1990 (PubMed).

Honer, Kaufmann, Davies: "Characterization of a synaptic antigen of interest in neuropsychiatric illness." in: Biological psychiatry, Vol. 31, Issue 2, pp. 147-58, 1992 (PubMed).

Validation Images
Catalog No. ABIN119030
456.50 $
Plus shipping costs $45.00
Quantity
Price
0.2 mg
456.50 $

Order hotline:

  • +1 877 302 8632
  • +1 888 205 9894 (TF)
Did you look for something else?