CD137 antibody

Catalog No. ABIN119157

The Rat Monoclonal anti-CD137 antibody (Clone LOB12) (ABIN119157) specifically detects CD137 in FACS. The antibody is reactive with Mouse samples.

Quick Overview for CD137 antibody (ABIN119157)

Target: CD137 (TNFRSF9) (Tumor Necrosis Factor Receptor Superfamily, Member 9 (TNFRSF9))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This CD137 antibody is un-conjugated

Application: Flow Cytometry (FACS)

Clone: LOB12

Product Details anti-CD137 Antibody

Specificity: This antibody recognises CD137 (the homologue of human 4-1BB protein).

Purification: Affinity Chromatography on Protein G.

Immunogen: Murine CD137 human Fc fusion protein.

Isotype: IgG2a

Application Details

Application Notes: Flow Cytometry: Use 10 μL of 1/10-1/50 diluted antibody to label 10^6 cells in 100 μL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.09 % Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for CD137

Target: CD137 (TNFRSF9) (Tumor Necrosis Factor Receptor Superfamily, Member 9 (TNFRSF9))

Alternative Name: CD137 / TNFRSF9

Background: CD137 is expressed by activated T lymphocytes, but not by resting cells.Synonyms: 4-1BB homolog, 4-1BB ligand receptor, CDw137, ILA, T-cell antigen 4-1BB homolog, T-cell antigen ILA, Tumor necrosis factor receptor superfamily member 9

Gene ID: 21942

NCBI Accession: NP_001070977

UniProt: P20334

Pathways: Cancer Immune Checkpoints