Killer Cell Lectin-Like Receptor Subfamily B, Member 1 (KLRB1) antibody (FITC)

Details for Product No. ABIN119271
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Antigen
Synonyms NKR-P1, KLRB1, 4930431A04Rik, Gm4696, Klrb1g, Klrb6, Ly-55, Ly55, NKR-P1G, Nkrp-1e, Nkrp1g, CD161, CLEC5B, NKR, NKR-P1A, NKRP1A, hNKR-P1A, Klrb1d, Klrb1f, Nkr-p1e
Reactivity
Human
(50), (37), (19), (2)
Host
Mouse
(92), (14)
Clonality (Clone)
Monoclonal ()
Conjugate
FITC
(21), (11), (10), (6), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Flow Cytometry (FACS)
(97), (36), (25), (24), (10), (10), (8), (7), (7), (7), (6), (6), (3)
Pubmed 2 references available
Quantity 0.1 mg
Shipping to United States (Change)
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Catalog No. ABIN119271
423.50 $
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Clone B199-2
Isotype IgG2b
Specificity This antibody recognises the human CD161 cell surface antigen, expressed by almost all NK cells and a small subset of CD3+ve T cells. Clone B199.2 recognises a similar epitope to the DX9 monoclonal antibody.
Purification Protein G chromatography
Alternative Name CD161 / KLRB1
Background CD161 is a homodimeric cell surface protein, comprising two chains of 40-44kD.
Alternate names: C-type lectin domain family 5 member B, CLEC5B, HNKR-P1a, Killer cell lectin-like receptor subfamily B member 1, NKRP1A, Natural killer cell surface protein P1A
Gene ID 3820
NCBI Accession NP_002249
UniProt Q12918
Research Area CD Antigens, Surface Receptors of Immune Cells
Application Notes Flow cytometry: neat - 1/10, use 10 ul of the suggested working dilution to label 10e6 cells in 100 ul. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 0.1 mg/mL
Buffer PBS, pH 7.4, containing 1% BSA and 0.09% sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing. This product is photosensitive and should be protected from light.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Expiry Date 12 months
Background publications Bennett, Zatsepina, Zamai et al.: "Definition of a natural killer NKR-P1A+/CD56-/CD16- functionally immature human NK cell subset that differentiates in vitro in the presence of interleukin 12." in: The Journal of experimental medicine, Vol. 184, Issue 5, pp. 1845-56, 1996 (PubMed).

Azzoni, Zatsepina, Abebe et al.: "Differential transcriptional regulation of CD161 and a novel gene, 197/15a, by IL-2, IL-15, and IL-12 in NK and T cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 161, Issue 7, pp. 3493-500, 1998 (PubMed).

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