HLA-A2 antibody (PE)

Catalog No. ABIN119578

This Mouse Monoclonal antibody specifically detects in FACS. It exhibits reactivity toward Human.

Quick Overview for HLA-A2 antibody (PE) (ABIN119578)

Target: HLA-A2

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: PE

Application: Flow Cytometry (FACS)

Clone: BB7-2

Product Details

Specificity: This antibody recognises the Human HLA-A2 histocompatability antigen. The epitope recognised by this antibody has been studied extensively and would appear to include the carboxy-terminus of the alpha-2 helix and a turn on one of the underlying beta strands. This antibody may be used for the Flow Cytometric Detection of HLA-A2 expression.

Cross-Reactivity (Details): Species reactivity (tested):Human.

Characteristics: Absorption / Emission: 488 nm / 575 nm

Purification: Affinity Chromatography on Protein G

Immunogen: Papain solubilised HLA-A2

Isotype: IgG2b

Application Details

Application Notes: Flow Cytometry (use 10 μL of neat antibody to label 10^6 cells or 100 μL whole blood).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Reconstitution: Restore with 1.0 mL distilled water.

Concentration: 0.1 mg/mL

Buffer: PBS, 0.09 % Sodium Azide, 1 % BSA and 5 % Sucrose

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody at 2-8 °C for one month or at -20 °C for longer.

Target Details

Target: HLA-A2

Alternative Name: HLA Class I A-2 alpha / HLA-A2

Target Type: Influenza Protein

Background: The major histocompatibility complex (MHC) is a cluster of genes that are important in the immune response to infections. In humans, this complex is referred to as the human leukocyte antigen (HLA) region. There are 3 major MHC class I proteins encoded by the HLA which are HLA A, HLA B and HLA C. The HLA A gene is part of the human HLA complex on chromosome 6 and there are a large number of variant alleles of this gene.Synonyms: A-2 alpha chain, HLA class I histocompatibility antigen, HLAA2, MHC class I antigen A-2

Gene ID: 100507703

NCBI Accession: XP_003119274

UniProt: P01892