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Details for Product No. ABIN121150

SET Domain Containing (Lysine Methyltransferase) 7 (SETD7) antibody

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Antigen
Synonyms KMT7, Set7, H3K4MT, Set7/9, mKIAA1717, 1600028F23Rik, SET7, SET7/9, SET9, set7, zgc:101860, zgc:92330
Reactivity
»Alternatives Human
Host
»Alternatives Mouse
Clonality (Clone) Monoclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Pubmed 1 reference available
Catalog no. ABIN121150
Quantity 0.1 mL
Price
401.50 $   Plus shipping costs $45.00
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Availability Will be delivered in 6 to 8 Business Days
Immunogen Recombinant human SET7/9 protein
Clone S4E5
Isotype IgG2b
Purification Affinity Chromatography on Protein G
Alternative Name SETD7 / SET9
Background Set7/9 is a histone methyltransferase (HMTase) that transfers methyl group to Lys4 of histone H3, in complex with S-adenosyl-L-methionine (AdoMet). The methylation of lysine residues of histones plays a critical role in the regulation of chromatin structure and gene expression. Acetylation, phosphorylation and methylation of the amino-terminal tails of histone are thought to be involved in the regulation of chromatin structure and function. The enzymes identified in the methylation of specific lysine residue on histones belong to the SET family with just one exception. Set7/9, unlike most other SET proteins, is exclusively a mono-methylase. Alternate Names: Histone Methyltransferase, SET-7, KMT7, SET7/9, KIAA1717, SET9.
UniProt Q8WTS6
Application Notes ELISA. Western blot (1:250 - 1:2,000), recommended starting dilution : 1:1,000. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 1.0 mg/mL
Buffer PBS, pH 7.4 containing 0.09% Sodium Azide as preservative. 0.09% Sodium Azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf Life: one year from despatch.
Expiry Date 12 months
Nishioka, Chuikov, Sarma et al.: "Set9, a novel histone H3 methyltransferase that facilitates transcription by precluding histone tail modifications required for heterochromatin formation." in: Genes & development, Vol. 16, Issue 4, pp. 479-89, 2002 (PubMed).

Alternatives for antigen "SET Domain Containing (Lysine Methyltransferase) 7 (SETD7)", type "Antibodies"
Hosts (39), (20)
Reactivities (61), (21), (16), (13), (12), (12), (1), (1)
Applications (45), (26), (16), (10), (5), (4), (3), (2), (2), (2), (2)
Conjugates (3), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (4), (3), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
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