Tumor Necrosis Factor Receptor Superfamily, Member 25 (TNFRSF25) antibody

Antigen: Tumor Necrosis Factor Receptor Superfamily, Member 25 (TNFRSF25)

Synonyms: DR3, TR3, DDR3, LARD, APO-3, TRAMP, WSL-1, WSL-LR, TNFRSF12, Wsl, Tnfrsf12, TNFRSF25

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Conjugate: Un-conjugated

Application: Western Blotting (WB)

Catalog no.: ABIN121506

Additional Information

Alternative name: TNFRSF25 / DR3 / TRAMP

UniProt: Q93038

Immunogen: Peptide sequence from amino terminus of human DR3 AA Sequence: QGGTRSPRCDCAGDFH

Cross-Reactivity: Human

Description: DR3 is a cell surface receptor with a death domain, with functional similarities to TNFR1 and Fas (CD95). The ligand for DR3 has very recently been identified and has been termed Apo-3L. DR3 itself has also been called Wsl-1, Apo-3, TRAMP and LARD, and functionally induces apoptosis and NF-KB activation. Alternate Names: TNFRSF25, APO3, DDR3, DR3, TNFRSF12, WSL, WSL1, WSL-1 protein, Apoptosis-mediating receptor DR3, Apoptosis-mediating receptor TRAMP, WSL protein, Apoptosis-inducing receptor AIR, Apo-3, Lymphocyte-associated receptor of death, LARD, DDR-3, DR-3, Tumor necrosis factor receptor superfamily member 25.

Application Details

Application Notes: Western blot: 1/500 - 1/1000. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.

Concentration: 1.0 mg/ml

Purification: Purified

Buffer: PBS containing 0.02% Sodium Azide

Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf Life: one year from despatch.

Restrictions: For Research Use only

Publications

Chinnaiyan, ORourke, Yu et al.: "Signal transduction by DR3, a death domain-containing receptor related to TNFR-1 and CD95." in: Science (New York, N.Y.), Vol. 274, Issue 5289, pp. 990-2, 1996 (PubMed).

Marsters, Sheridan, Pitti et al.: "Identification of a ligand for the death-domain-containing receptor Apo3." in: Current biology : CB, Vol. 8, Issue 9, pp. 525-8, 1998 (PubMed).