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GDNF Family Receptor alpha 2 (GFRA2) antibody

Antigen

GDNF Family Receptor alpha 2 (GFRA2)
Synonyms NTNRA, RETL2, TRNR2, GDNFRB, NRTNR-ALPHA, DKFZP459C0228, GFRA2, Retl2, NTNRALPHA, MGC142640, ntnra, retl2, trnr2, gdnfrb, nrtnr-alpha, DKFZp459O181
Clonality Polyclonal
Host
Alternatives

Rabbit
Reactivity
Alternatives

Human
Conjugate
Alternatives Un-conjugated
Application
Alternatives Western Blotting (WB), Immunofluorescence (IF)
2 references available
Catalog no. ABIN121837
Quantity 0.1 mg  (0.5 mg/ml)
Price 407.00 $   Plus shipping costs $45.00
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Additional Information
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Alternative name GFRA2 / GDNFR-beta
UniProt O00451
Immunogen Synthetic peptide from C-terminus of human GFR alpha-2
Cross-Reactivity Human, Mouse (Murine), Rat (Rattus)
Description Neurturin is a member of the GDNF family, and has an important role in the control of vertebrate neuron survival and differentiation. GRF alpha-2 is a 52kD glycoprotein, and is a GPI-linked cell surface receptor.
Specificity This antibody recognises the cell surface receptor for neurturin, which was recently designated as GFR alpha-2.

Application Details
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Application Notes Western Blot: 1/1000. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Concentration 0.5 mg/ml
Purification Purified
Buffer PBS containing 0.02% Sodium Azide
Storage Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf Life: one year from despatch.
Restrictions For Research Use only

Publications
Application Details Alternatives back to top

Klein, Sherman, Ho et al.: "A GPI-linked protein that interacts with Ret to form a candidate neurturin receptor." in: Nature, Vol. 387, Issue 6634, pp. 717-21, 1997 (PubMed).

Buj-Bello, Adu, Piñón et al.: "Neurturin responsiveness requires a GPI-linked receptor and the Ret receptor tyrosine kinase." in: Nature, Vol. 387, Issue 6634, pp. 721-4, 1997 (PubMed).

Alternatives
Application Details Publications back to top

Alternatives for antigen "GDNF Family Receptor alpha 2 (GFRA2)", type "Antibodies"
Hosts Rabbit (39), Goat (4)
Reactivities Human (39), Mouse (Murine) (27), Rat (Rattus) (27), Cow (Bovine) (20), Dog (Canine) (20), Chicken (19), Horse (Equine) (18), Cat (Feline) (1)
Applications Western Blotting (WB) (28), ELISA (17), Immunofluorescence (IF) (17), Immunohistochemistry (IHC) (5), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (5), Immunocytochemistry (ICC) (3), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (3), Immunoprecipitation (IP) (2), Immunoelectron Microscopy (IEM) (1), Immunohistochemistry (Fixed) (IHC (fx)) (1)
Conjugates Biotin (2), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1)
Epitopes C-Term (4), AA 377-391 (2), AA 376-390 (1), Center (1), Internal Region (1), Middle Region (1), internal (1)