TNFSF13 antibody (AA 196-210)

Catalog No. ABIN121878

The Rabbit Polyclonal anti-TNFSF13 antibody (ABIN121878) specifically detects TNFSF13 in WB. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for TNFSF13 antibody (AA 196-210) (ABIN121878)

Target: TNFSF13 (Tumor Necrosis Factor (Ligand) Superfamily, Member 13 (TNFSF13))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TNFSF13 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TNFSF13 Antibody

Binding Specificity: AA 196-210

Specificity: This antibody is specific for the CD256 cell surface antigen, also known as A Proliferation Inducing Ligand (APRIL).

Purification: Affinity chromatography

Immunogen: Synthetic peptide corresponding to amino acids 196 to 210 of human CD256

Application Details

Application Notes: Western Blot: 1 μg/mL - 4 μg/mL, this antibody detects a band approximately 27 kD in Jurkat cell lysates.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf Life: one year from despatch.

Expiry Date: 12 months

Target Details for TNFSF13

Target: TNFSF13 (Tumor Necrosis Factor (Ligand) Superfamily, Member 13 (TNFSF13))

Alternative Name: CD256 / APRIL

Background: CD256 is a member of the tumour necrosis factor family, which is expressed in B cells and several tumour cells. The protein is involved in stimulating B and T cell proliferation, triggering humoral immune responses, activating NF-kappaB and inducing cell death. CD256 is thought to play a role in autoimmune diseases and cancer.Synonyms: A proliferation-inducing ligand, TALL-2, TALL2, TNF- and APOL-related leukocyte expressed ligand 2, TNF-related death ligand 1, TNFSF13, TRDL-1, Tumor necrosis factor ligand superfamily member 13, ZTNF2

Gene ID: 8741

UniProt: O75888

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response