CHRM5 antibody

Catalog No. ABIN122329

This Rabbit Polyclonal antibody specifically detects CHRM5 in IHC (p). It exhibits reactivity toward Human.

Quick Overview for CHRM5 antibody (ABIN122329)

Target: CHRM5 (Cholinergic Receptor, Muscarinic 5 (CHRM5))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHRM5 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-CHRM5 Antibody

Specificity: Reacts with Muscarinic Acetylcholine Receptor M5 (family: GPCR, subfamily: Acetylcholine)

Purification: Peptide immunogen affinity column

Immunogen: Synthetic peptide - KLH conjugated

Application Details

Application Notes: Immunohistochemistry with formalin fixed paraffin embedded tissues: 6 μg/mL Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100 °C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1x TBS with Tween (TBST) for 1 min. at room temperature.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. Further Comments: This product was originally produced by MBL International.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS, pH 7.7, containing 0.01 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-80 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -70 °C for longer. Avoid repeated freezing and thawing.
Shelf Life: one year from despatch.

Expiry Date: 12 months

Target Details for CHRM5

Target: CHRM5 (Cholinergic Receptor, Muscarinic 5 (CHRM5))

Alternative Name: Muscarinic Acetylcholine Receptor M5

Background: Muscarinic cholinergic receptor M5 is an Acetylcholine Receptor that is active during embryonic development. It is coupled to phosphoinositide degradation and to the activation of mitogen-activated protein kinase (MAPK). The M5 receptor has been reported to be expressed in blood, brain, and ovary. ESTs have been isolated from human testis and placenta libraries.Synonyms: CHRM5, mAChR M5, mAChR-M5

Gene ID: 1133

UniProt: P08912

Pathways: Synaptic Membrane