CHRM5 antibody (AA 281-330)

Catalog No. ABIN1535647

The Rabbit Polyclonal anti-CHRM5 antibody is suitable to detect CHRM5 in samples from Human, Mouse and Rat. It has been validated for WB, ELISA and IF.

Quick Overview for CHRM5 antibody (AA 281-330) (ABIN1535647)

Target: CHRM5 (Cholinergic Receptor, Muscarinic 5 (CHRM5))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHRM5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Product Details anti-CHRM5 Antibody

Binding Specificity: AA 281-330

Purpose: mAChR M5 Antibody

Specificity: MAChR M5 Polyclonal Antibody detects endogenous levels of mAChR M5 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human CHRM5. AA range:281-330

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:40000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for CHRM5

Target: CHRM5 (Cholinergic Receptor, Muscarinic 5 (CHRM5))

Alternative Name: CHRM5

Background:

Synonyms: CHRM5, Muscarinic acetylcholine receptor M5

Background: The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The clinical implications of this receptor are unknown, however, stimulation of this receptor is known to increase cyclic AMP levels. [provided by RefSeq, Jul 2008],

Gene Name: CHRM5

Protein Name: Muscarinic acetylcholine receptor M5

Molecular Weight: 60 kDa

Gene ID: 1133

OMIM: 118496

UniProt: P08912

Pathways: Synaptic Membrane