HCRTR1 antibody

Catalog No. ABIN122603

The Rabbit Polyclonal anti-HCRTR1 antibody has been validated for IHC (p). It is suitable to detect HCRTR1 in samples from Human, Rat and Mouse.

Quick Overview for HCRTR1 antibody (ABIN122603)

Target: HCRTR1 (Hypocretin (Orexin) Receptor 1 (HCRTR1))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HCRTR1 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-HCRTR1 Antibody

Specificity: Reacts with Orexin Receptor 1 (OX1R) (family: GPCR, subfamily: Orexin)

Purification: Peptide immunogen affinity column

Immunogen: Synthetic peptide - KLH conjugated

Application Details

Application Notes: Immunohistochemistry on paraffin embedded sections: 6,8 μg/mL Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100 °C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1x TBS with Tween (TBST) for 1 min. at room temperature.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. Further Comments: This product was originally produced by MBL International.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS, pH 7.7, containing 0.01 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-80 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -70 °C for longer. Avoid repeated freezing and thawing.
Shelf Life: one year from despatch.

Expiry Date: 12 months

Target Details for HCRTR1

Target: HCRTR1 (Hypocretin (Orexin) Receptor 1 (HCRTR1))

Alternative Name: Orexin Receptor Type 1

Background: OX1R is an Orexin Receptor selective for orexin A. This receptor participates in the feedback mechanism that regulates feeding behavior and sleep. When activated, OX1R stimulates appetite. OX1R has been implicated in narcolepsy, a sleep/wake disorder. Orexin receptor 1 expression has been documented in adrenal and brain. ESTs have been isolated from brain, pancreas, and lung/spleen libraries.Synonyms: HCRTR1, Hypocretin receptor type 1, Ox1r

Gene ID: 3061

UniProt: O43613

Pathways: Feeding Behaviour