PAK6 antibody (Linker Domain)

Catalog No. ABIN122606

The Rabbit Polyclonal anti-PAK6 antibody is suitable to detect PAK6 in samples from Human. It has been validated for IHC (p).

Quick Overview for PAK6 antibody (Linker Domain) (ABIN122606)

Target: PAK6 (P21-Activated Kinase 6 (PAK6))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PAK6 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-PAK6 Antibody

Binding Specificity: Linker Domain

Specificity: Reacts with P21-Activated Kinase 6 (PAK6) (family: Protein Kinase, subfamily: PAK (STE20))

Characteristics: Synonyms: p21-activated kinase 6, PAK-6, Serine/threonine-protein kinase PAK 6, PAK5, PAK-5

Purification: Peptide immunogen affinity column

Immunogen: Synthetic peptide - KLH conjugatedEpitope: Linker domain of humanGenename: PAK6

Application Details

Application Notes: Immunohistochemistry on paraffin embedded sections: 3,5 μg/mLAntigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100C for 20 min. Remove fromheat and let stand at room temperature in buffer for 20 min. Rinse in 1x TBS with Tween(TBST) for 1 min. at room temperature.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS, pH 7.7, containing 0.01 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-80 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -70 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for PAK6

Target: PAK6 (P21-Activated Kinase 6 (PAK6))

Alternative Name: PAK6

Background: PAK6, a PAK (STE20) type protein kinase, contains a N-terminal Cdc42/Rac interactive binding (CRIB) motif and a C-terminal kinase domain. The protein has been shown to bind to GTP-Cdc42 and GTP-Rac, however, in contrast to most PAKs, kinase activity was not stimulated by Cdc42 or Rac, but could be stimulated by androgen receptor (AR) binding. PAK6 protein also has been shown to bind to estrogen receptor alpha. PAK6 also has been called P21-Activated Kinase 5 (PAK5), however, PAK5 is a distinct gene found on chromosome 20 p12.2. PAK6 expression has been documented in normal human brain, breast, prostate and testis. ESTs have been isolated from several tissue libraries, including normal brain and testis and cancerous cervix and smooth muscle.Synonyms: PAK-5, PAK-6, PAK5, Serine/threonine-protein kinase PAK 6, p21-activated kinase 6

Gene ID: 56924

UniProt: Q9NQU5