CYR61 antibody

Catalog No. ABIN127279

This Rabbit Polyclonal antibody specifically detects CYR61 in WB. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for CYR61 antibody (ABIN127279)

Target: CYR61 (Cysteine-Rich, Angiogenic Inducer, 61 (CYR61))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CYR61 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CYR61 Antibody

Specificity: The antibody detects the full length and cleaved form of Cyr61 protein.

Purification: Purified

Immunogen: Synthetic peptide surrounding aa 166 of mouse Cyr61

Application Details

Application Notes: The antibody can be used for Western blotting (0.5-4 μg/mL). Jurkat cell lysate and mousesmall intestine tissue lysate can be used as positive controls.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: PBS, pH 7.2, containing 30 % glycerol and 0.01 % thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C/-80 °C

Storage Comment: Store (in aliquots) at -20 °C to -70 °C.

Target Details for CYR61

Target: CYR61 (Cysteine-Rich, Angiogenic Inducer, 61 (CYR61))

Alternative Name: CYR61

Background: Cyr61 is a member of angiogenic and vasculogenic regulators designated CCN proteins, which includes CTGF, Cyr61 homolog, Fisp2. Cyr61 functions as an angiogenic inducer, stimulating cell adhesion and migration and promotes DNA synthesis of human vascular endothelial cells. Elevated expression of Cyr61 is observed during vessel growth, wound healing and chondrocyte differentiation.Synonyms: CCN family member 1, CCN1, Cysteine-rich angiogenic inducer 61, GIG1, IBP10, IGF-binding protein 10, IGFBP10, Insulin-like growth factor-binding protein 10

Gene ID: 3491

NCBI Accession: NP_001545

UniProt: O00622

Pathways: Positive Regulation of Endopeptidase Activity, Growth Factor Binding