SLC5A1 antibody

Catalog No. ABIN127319

The Rabbit Polyclonal anti-SLC5A1 antibody is suitable to detect SLC5A1 in samples from Human. It has been validated for WB and IHC (fro).

Quick Overview for SLC5A1 antibody (ABIN127319)

Target: SLC5A1 (Solute Carrier Family 5 (Sodium/glucose Cotransporter), Member 1 (SLC5A1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC5A1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-SLC5A1 Antibody

Specificity: The antibody detects 73 kDa SGLT-1 from Human samples and in a lesser extent Mouse and Rat. A ~50 kDa cleavage fragment can also be detected in Jurkat cell lysate.

Purification: Affinity Chromatography on Protein A.

Immunogen: Synthetic peptide surrounding amino acid 594 of human SGLT-1

Application Details

Application Notes: Western Blot: 0.5-4 μg/mL. Jurkat cell lysate can be used as a Positive Control.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: PBS, pH 7.2 containing 30 % Glycerol, 0.01 % Thimerosal, 0.5 % BSA

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C/-80 °C

Storage Comment: Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.

Target Details for SLC5A1

Target: SLC5A1 (Solute Carrier Family 5 (Sodium/glucose Cotransporter), Member 1 (SLC5A1))

Alternative Name: SGLT1 / SLC5A1

Background: Glucose transporters are integral membrane proteins that mediate the transport of glucose and structurally related substances across cellular membranes. Two families of glucose transporter have been identified: the facilitated diffusion glucose transporter family (GLUT family), also known as uniporters and the sodium dependent glucose transporter family (SGLT family) also known as cotransporters or symporters. The SGLT1 gene encodes a protein that is involved in the active transport of glucose and galactose into eukaryotic and some prokaryotic cells.Synonyms: High affinity sodium-glucose cotransporter, NAGT, Na(+)/glucose cotransporter 1, Sodium/glucose cotransporter 1, Solute carrier family 5 member 1

Gene ID: 6523

NCBI Accession: NP_000334

UniProt: P13866