TCRgd antibody

Catalog No. ABIN135302

The Hamster Monoclonal anti- antibody has been validated for FACS. It is suitable to detect in samples from Mouse.

Quick Overview for TCRgd antibody (ABIN135302)

Target: TCRgd

Reactivity: Mouse

Host: Hamster

Clonality: Monoclonal

Conjugate: Un-conjugated

Application: Flow Cytometry (FACS)

Clone: UC7-13D5

Product Details

Specificity: Mouse TCR

Characteristics: Hamster Anti-Mouse TCRgd-UNLB

Purification: Purified

Immunogen: Mouse T cell clone G8

Isotype: IgG

Application Details

Application Notes:

• Applications: FC - Quality tested , IP - Reported in literature , Costim - Reported in literature , Depletion - Reported in literature
• Working Dilutions: Flow Cytometry FITC, BIOT, and AF488 conjugates 1 g/106 cells PE and SPRD conjugates 0.3 g/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L

Comment:

In vivo depletion of gd TCR-expressing T cell

Sample Volume: 1 mL

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: 0.5 mg of purified immunoglobulin in 1.0 mL of borate buffered saline,  pH 8.2. No preservatives or amine-containing buffer salts added

Preservative: Without preservative

Handling Advice: Each reagent is stable for the period shown on the bottle label if stored as directed.

Storage: 4 °C

Storage Comment: Store at 2-8°C

Target Details

Target: TCRgd

Background: The TCR heterodimer of the CD3/T-cell receptor complex is clonotypic and consists of Ig-like variable and constant domains.1 It is expressed during thymopoiesis and on the small subpopulation of TCR-expressing T lymphocytes in the periphery. The majority of T cells present in some epithelial tissues are + and have limited receptor diversity. The TCR heterodimer recognizes peptide antigen bound to MHC antigens, and subsequent signal transduction mediated by the invariant chains leads to T cell activation.