CD16 antibody

Catalog No. ABIN135754

This Mouse Monoclonal antibody specifically detects CD16 in FACS. It exhibits reactivity toward Humanand has been mentioned in 1 publication.

Quick Overview for CD16 antibody (ABIN135754)

Target: CD16

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD16 antibody is un-conjugated

Application: Flow Cytometry (FACS)

Clone: GRM1

Product Details anti-CD16 Antibody

Specificity: Human CD16, Mr 50-65 kDa

Characteristics: Mouse Anti-Human CD16-UNLB

Purification: Purified

Immunogen: Mononuclear cells from a prolymphocytic B-leukemia

Isotype: IgG2a

Application Details

Application Notes:

• Applications: FC - Quality tested , IHC-FS - Reported in literature , IP - Reported in literature , WB - Reported in literature , ELISA - Reported in literature , CMCD - Reported in literature
• Working Dilutions: Flow Cytometry Purified (UNLB) antibody 1 g/106 cells FITC, BIOT, PE, SPRD, AF488, AF647, and AF700 conjugates 10 L/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L

Sample Volume: 1 mL

Restrictions: For Research Use only

Handling

Concentration: 0.1 mg/mL

Buffer: 0.1 mg of purified immunoglobulin in 1.0 mL of borate buffered saline,  pH 8.2. No preservatives or amine-containing buffer salts added

Preservative: Without preservative

Handling Advice: Each reagent is stable for the period shown on the bottle label if stored as directed.

Storage: 4 °C

Storage Comment: Store at 2-8°C

References for anti-CD16 antibody (ABIN135754)

Mesquita, Fintelman-Rodrigues, Sacramento, Abrantes, Costa, Temerozo, Siqueira, Bou-Habib, Souza: "HIV-1 and Its gp120 Inhibits the Influenza A(H1N1)pdm09 Life Cycle in an IFITM3-Dependent Fashion." in: PLoS ONE, Vol. 9, Issue 6, pp. e101056, (2014) (PubMed).

Target Details for CD16

Target: CD16

Alternative Name: CD16

Background: CD16, a member of the immunoglobulin superfamily, is a 50-65 kDa glycoprotein found as both a transmembrane and GPI-linked form. The transmembrane form of CD16 is expressed on NK cells, granulocytes, macrophages, and mast cells but not on eosinophils. The GPI-anchored type of CD16 is found only on neutrophils. CD16 is involved in NK activation and signal transduction.

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process