GABRR2 antibody (AA 161-260) (AbBy Fluor® 555)

Catalog No. ABIN1395071

The Rabbit Polyclonal anti-GABRR2 antibody is suitable to detect GABRR2 in samples from Human. It has been validated for IF (cc) and IF (p).

Quick Overview for GABRR2 antibody (AA 161-260) (AbBy Fluor® 555) (ABIN1395071)

Target: GABRR2 (gamma-aminobutyric Acid (GABA) Receptor, rho 2 (GABRR2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GABRR2 antibody is conjugated to AbBy Fluor® 555

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-GABRR2 Antibody (AbBy Fluor® 555)

Binding Specificity: AA 161-260

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Horse,Chicken,Zebrafish

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GABRR2

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for GABRR2

Target: GABRR2 (gamma-aminobutyric Acid (GABA) Receptor, rho 2 (GABRR2))

Alternative Name: GABRR2

Background:

Synonyms: GABA receptor Rho 2 subunit, GABAA receptor, GABAA receptor subunit rho-2, GABAC receptor, GABRR 2, Gamma aminobutyric acid receptor rho 2 subunit [Precursor], Gamma-aminobutyric acid GABA A receptor, rho 2, Gamma-aminobutyric acid receptor subunit rho-2, Rho 2 GABA receptor, GBRR2_HUMAN.

Background: Gamma-aminobutyric acid (GABA) receptors are pentameric membrane proteins that operate GABA-gated chloride channels and inhibit neurotransmission in the central nervous system. The rho receptor subunits do not exhibit sensitivity to typical GABA receptor modulators such as bicuculline, hexobarbital, and diazepam. While the rho 1 subunit localizes specifically to the retina, rho 2 expresses in all regions of the brain, though levels were still highest in the retina, implying a role for both subunits in visual pathways.