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Protein Regulator of Cytokinesis 1 (PRC1) (Middle Region) antibody

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Synonyms cb212, prc1, prc1l, zgc:55982, zgc:86918, MGC68845, zgc:55664, ase1, ASE1, D7Ertd348e
Middle Region
(5), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Human, Mouse (Murine), Rat (Rattus)
(48), (22), (22), (1), (1)
(41), (9)
(1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Enzyme Immunoassay (EIA), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(35), (17), (11), (9), (8), (6), (3), (2), (1), (1)
Pubmed 1 reference available
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Quantity 0.1 mg
Shipping to United States ( )
Availability Will be delivered in 6 to 8 Business Days
Immunogen 19 amino acid synthetic peptide near the center of Human PRC1
Isotype IgG
Cross-Reactivity (Details) Species reactivity (tested):Human, Mouse, Rat.
Purification Affinity chromatography purified via peptide column
Alternative Name PRC1 (PRC1 Antibody Abstract)
Background PRC1 (Protein Regulator of Cytokinesis 1) is a key regulator of cytokinesis and has been identified as a substrate for several cyclin-dependent kinases (CDKs). High levels of PRC1 expression occurs during S and G2/M and drops dramatically after mitosis exit and G1 entry. It is located in the nucleus during interphase and binds to the midzone of mitotic spindles during anaphase and is localized to the cell midbody during cytokinesis. Depletion of PRC1 has been shown to prevent cellular cleavage, but it has no effect on nuclear division, demonstrating the importance of PRC1 in mitosis.Synonyms: ASE1, Protein regulator of cytokinesis 1
Gene ID 9055
NCBI Accession NP_003972
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Concentration 1.0 mg/mL
Buffer PBS containing 0.02 % Sodium Azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Protein Regulator of Cytokinesis 1 (PRC1) (Middle Region) antibody (ABIN1449936) Immunohistochemistry of PRC1 in mouse skeletal muscle tissue with PRC1 antibody at 2....
Western Blotting (WB) image for anti-Protein Regulator of Cytokinesis 1 (PRC1) (Middle Region) antibody (ABIN1449936) Western blot analysis of PRC1 in human skeletal muscle tissue lysate with Prc1 antibo...
Background publications Jiang, Jimenez, Wells et al.: "PRC1: a human mitotic spindle-associated CDK substrate protein required for cytokinesis." in: Molecular cell, Vol. 2, Issue 6, pp. 877-85, 1999 (PubMed).

Catalog No. ABIN1449936
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