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RGS22 antibody (N-Term)

RGS22 Reactivity: Human, Mouse, Rat WB, IF, EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN1449995
  • Target See all RGS22 Antibodies
    RGS22 (Regulator of G-Protein Signaling 22 (RGS22))
    Binding Specificity
    • 7
    • 6
    • 6
    • 6
    • 5
    • 3
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 30
    • 8
    • 3
    • 2
    • 2
    • 1
    Human, Mouse, Rat
    Host
    • 30
    Rabbit
    Clonality
    • 30
    Polyclonal
    Conjugate
    • 10
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This RGS22 antibody is un-conjugated
    Application
    • 20
    • 19
    • 15
    • 11
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
    Purification
    Affinity chromatography purified via peptide column
    Immunogen
    A 19 amino acid synthetic peptide near the amino terminus of Human RGS22
    Isotype
    IgG
    Top Product
    Discover our top product RGS22 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    PBS containing 0.02 % Sodium Azide as preservative
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    RGS22 (Regulator of G-Protein Signaling 22 (RGS22))
    Alternative Name
    RGS22 (RGS22 Products)
    Synonyms
    PRTD-NY2 antibody, RGD1565493 antibody, regulator of G protein signaling 22 antibody, regulator of G-protein signaling 22 antibody, regulator of G-protein signalling 22 antibody, RGS22 antibody, Rgs22 antibody
    Background
    Regulator of G-protein signaling (RGS) proteins contain an 120 amino acid conserved domain, termed the RGS domain, that acts as a GTPase-activating protein that acts to reduce the signal transmitted by the receptor-activated G-alpha subunit (1,2). RGS22 is a recently identified member of this family that localizes to the testis and can interact with guanine nucleotide binding proteins alpha 11, 12, and 13 (GNA11, GNA12, and GNA13). While RGS22 has been postulated to play a role in spermiogenesis in the testis, it is also expressed in several cancer cell lines with an epithelial origin and associated with cancer metastasis. Its overexpression in a highly metastatic cancer causes a decrease in cell migration and a reduction of the invasive potential of the cells, suggesting that RGS22 may be a potential prognostic biomarker for metastasis.Synonyms: Regulator of G-protein signaling 22
    Molecular Weight
    139 kDa
    Gene ID
    26166
    NCBI Accession
    NP_056483
    Pathways
    Regulation of G-Protein Coupled Receptor Protein Signaling
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