CASKIN1 antibody (Middle Region)

Catalog No. ABIN1449997

This Rabbit Polyclonal antibody specifically detects CASKIN1 in WB and EIA. It exhibits reactivity toward Human.

Quick Overview for CASKIN1 antibody (Middle Region) (ABIN1449997)

Target: CASKIN1 (CASK Interacting Protein 1 (CASKIN1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CASKIN1 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-CASKIN1 Antibody

Binding Specificity: Middle Region

Purification: Affinity chromatography purified via peptide column

Immunogen: A 17 amino acid synthetic peptide near the center of Human CASKIN1

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for CASKIN1

Target: CASKIN1 (CASK Interacting Protein 1 (CASKIN1))

Alternative Name: CASKIN1

Background: Calcium/calmodulin-dependent serine protein kinase (CASK) is a conserved multi-domain scaffolding protein involved in brain development, synapse formation, and establishment of cell polarity. CASKINs (CASK interacting proteins) interact with CASK and is thought to play a role in CASK function, specifically by coupling CASK to distinct downstream effectors. CASKIN1 is a multidomain protein containing six N-terminal ankyrin repeats, one SH3 domain, and two sterile alpha motif domains followed by a long proline-rich sequence and a short conserved C-terminal domain. CASKIN1 coassembles with CASK on the cytoplasmic tail of neurexin 1, suggesting that CASKIN and CASK coat the cytoplasmic tails of neurexins and other cell-surface proteins.Synonyms: ANKS5A, CASK interacting protein 1, Caskin-1

Molecular Weight: 157 kDa

Gene ID: 57524

NCBI Accession: NP_065815