CASKIN1 antibody (AA 720-770)

Catalog No. ABIN6991736

Product Details anti-CASKIN1 Antibody

Target: CASKIN1 (CASK Interacting Protein 1 (CASKIN1))

Binding Specificity: AA 720-770

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CASKIN1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Specificity: CASKIN1 antibody is predicted to not cross-react with other CASKIN family members.

Purification: CASKIN1 Antibody is affinity chromatography purified via peptide column.

Immunogen: CASKIN1 antibody was raised against a 17 amino acid synthetic peptide near the center of human CASKIN1. The immunogen is located within amino acids 720 - 770 of CASKIN1.

Isotype: IgG

Application Details

Application Notes: CASKIN1 antibody can be used for detection of CASKIN1 by Western blot at 1 μ,g/mL.

Antibody validated: Western Blot in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: CASKIN1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: CASKIN1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for CASKIN1

Target: CASKIN1 (CASK Interacting Protein 1 (CASKIN1))

Alternative Name: CASKIN1 (CASKIN1 Products)

Synonyms: ANKS5A antibody, 3300002N10Rik antibody, C130061I24 antibody, C630036E02Rik antibody, mKIAA1306 antibody, CASK interacting protein 1 antibody, CASKIN1 antibody, Caskin1 antibody

Background: CASKIN1 Antibody: Calcium/calmodulin-dependent serine protein kinase (CASK) is a conserved multi-domain scaffolding protein involved in brain development, synapse formation, and establishment of cell polarity. CASKINs (CASK interacting proteins) interact with CASK and is thought to play a role in CASK function, specifically by coupling CASK to distinct downstream effectors. CASKIN1 is a multidomain protein containing six N-terminal ankyrin repeats, one SH3 domain, and two sterile alpha motif domains followed by a long proline-rich sequence and a short conserved C-terminal domain. CASKIN1 coassembles with CASK on the cytoplasmic tail of neurexin 1, suggesting that CASKIN and CASK coat the cytoplasmic tails of neurexins and other cell-surface proteins.

Molecular Weight: Predicted: 157 kDa

Observed: 160 kDa

Gene ID: 57524

NCBI Accession: NP_065815

UniProt: Q8WXD9