Tctex1 Domain Containing 4 (TCTEX1D4) (N-Term) antibody

Details for Product No. ABIN1450005
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Antigen
Synonyms 4833401D15Rik, N22.1, Tctex-2-beta
Epitope
N-Term
(6), (1), (1), (1)
Reactivity
Human, Mouse (Murine), Rat (Rattus)
(8), (4), (4)
Host
Rabbit
(8)
Clonality
Polyclonal
Application
Immunocytochemistry (ICC), Immunofluorescence (IF), ELISA, Western Blotting (WB)
(8), (4), (4), (1)
Pubmed 5 references available
Catalog no. ABIN1450005
Quantity 0.1 mg
Price
401.50 $   Plus shipping costs $45.00
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Availability Will be delivered in 6 to 8 Business Days

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  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen 19 amino acid synthetic peptide near the amino terminus of Human TCTEX1D4
Isotype IgG
Specificity This antibody is predicted not to cross-react with other members of the TCTEX-type family.
Purification Affinity chromatography purified via peptide column
Alternative Name TCTEX1D4
Background Dyneins are multi-subunit, high molecular weight ATPases that interact with microtubules to generate force by converting the chemical energy of ATP into the mechanical energy of movement. Cytoplasmic or axonemal Dynein is an approximately 12 subunit complex of two heavy chains, two intermediate chains to anchor Dynein to its cargo, four smaller intermediate chains and several light chains. It performs functions necessary for cell survival such as organelle transport and centrosome assembly. TCTEX1 is a cytoplasmic dynein light chain found in a complex with Na+ CP type X (SCN10A). TCTEX1D4, also called TCTEX2 beta, interacts with different members of the TGF-beta receptor family, and when overexpressed, inhibits TGF-beta signaling.
Alternate names: RP11-269F19.9, Tctex-2-beta, Tctex1 domain-containing protein 4
Gene ID 343521
NCBI Accession NP_001013654
Research Area Stem Cells
Restrictions For Research Use only
Format Liquid
Concentration 1.0 mg/mL
Buffer PBS containing 0.02% Sodium Azide as preservative
Preservative Sodium azide
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Expiry Date 12 months
Background publications Watanabe, Fujiwara, Shimizu et al.: "Cloning, expression, and mapping of TCTEL1, a putative human homologue of murine Tcte1, to 6q." in: Cytogenetics and cell genetics, Vol. 73, Issue 1-2, pp. 153-6, 1996 (PubMed).

He, Francis, Myers et al.: "Role of cytoplasmic dynein in the axonal transport of microtubules and neurofilaments." in: The Journal of cell biology, Vol. 168, Issue 5, pp. 697-703, 2005 (PubMed).

Li, Lee, Cooper: "NudEL targets dynein to microtubule ends through LIS1." in: Nature cell biology, Vol. 7, Issue 7, pp. 686-90, 2005 (PubMed).

Chuang, Yeh, Bollati et al.: "The dynein light chain Tctex-1 has a dynein-independent role in actin remodeling during neurite outgrowth." in: Developmental cell, Vol. 9, Issue 1, pp. 75-86, 2005 (PubMed).

Meng, Lux, Holloschi et al.: "Identification of Tctex2beta, a novel dynein light chain family member that interacts with different transforming growth factor-beta receptors." in: The Journal of biological chemistry, Vol. 281, Issue 48, pp. 37069-80, 2006 (PubMed).

Hosts (8)
Reactivities (8), (4), (4)
Applications (8), (4), (4), (1)
Epitopes (6), (1), (1), (1)
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
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