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Details for Product No. ABIN1450007

Tctex1 Domain Containing 2 (TCTEX1D2) (N-Term) antibody

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Antigen
Synonyms 0610012D17Rik, 2410011K15Rik, RGD1563597
Epitope
»Alternatives N-Term
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Clonality Polyclonal
Application
»Alternatives Immunocytochemistry (ICC), Immunofluorescence (IF), ELISA, Western Blotting (WB)
Pubmed 5 references available
Catalog no. ABIN1450007
Quantity 0.1 mg
Price
390.50 $   Plus shipping costs $45.00
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Availability Will be delivered in 6 to 8 Business Days
Immunogen 16 amino acid synthetic peptide near the amino terminus of Human TCTEX1D2
Isotype IgG
Specificity This antibody is predicted not to cross-react with other members of the TCTEX-type family.
Purification Affinity chromatography purified via peptide column
Alternative Name TCTEX1D2
Background Dyneins are multi-subunit, high molecular weight ATPases that interact with microtubules to generate force by converting the chemical energy of ATP into the mechanical energy of movement. Cytoplasmic or axonemal Dynein is an approximately 12 subunit complex of two heavy chains, two intermediate chains to anchor Dynein to its cargo, four smaller intermediate chains and several light chains. It performs functions necessary for cell survival such as organelle transport and centrosome assembly. TCTEX1 is a cytoplasmic dynein light chain found in a complex with Na+ CP type X (SCN10A). TCTEX1D2, also called TCTEX1 domain containing 2, belongs to the dynein light chain TCTEX-type family. Its function is still under investigation.
Alternate names: Tctex1 domain-containing protein 2
Gene ID 255758
NCBI Accession NP_689986
Restrictions For Research Use only
Format Liquid
Concentration 1.0 mg/mL
Buffer PBS containing 0.02% Sodium Azide as preservative
Preservative Sodium azide
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Expiry Date 12 months
Background publications Watanabe, Fujiwara, Shimizu et al.: "Cloning, expression, and mapping of TCTEL1, a putative human homologue of murine Tcte1, to 6q." in: Cytogenetics and cell genetics, Vol. 73, Issue 1-2, pp. 153-6, 1996 (PubMed).

He, Francis, Myers et al.: "Role of cytoplasmic dynein in the axonal transport of microtubules and neurofilaments." in: The Journal of cell biology, Vol. 168, Issue 5, pp. 697-703, 2005 (PubMed).

Li, Lee, Cooper: "NudEL targets dynein to microtubule ends through LIS1." in: Nature cell biology, Vol. 7, Issue 7, pp. 686-90, 2005 (PubMed).

Chuang, Yeh, Bollati et al.: "The dynein light chain Tctex-1 has a dynein-independent role in actin remodeling during neurite outgrowth." in: Developmental cell, Vol. 9, Issue 1, pp. 75-86, 2005 (PubMed).

Pfister, Fisher, Gibbons et al.: "Cytoplasmic dynein nomenclature." in: The Journal of cell biology, Vol. 171, Issue 3, pp. 411-3, 2005 (PubMed).

Alternatives for antigen "Tctex1 Domain Containing 2 (TCTEX1D2)", type "Antibodies"
Hosts (8)
Reactivities (7)
Applications (7), (4), (4)
Epitopes (7)
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