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TSPY1 antibody (C-Term, Isoform 1)

TSPY1 Reactivity: Human, Mouse WB, EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN1450020
  • Target See all TSPY1 Antibodies
    TSPY1 (Testis Specific Protein, Y-Linked 1 (TSPY1))
    Binding Specificity
    • 12
    • 11
    • 2
    • 2
    • 1
    • 1
    • 1
    C-Term, Isoform 1
    Reactivity
    Human, Mouse
    Host
    • 28
    • 3
    Rabbit
    Clonality
    • 29
    • 2
    Polyclonal
    Conjugate
    • 14
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TSPY1 antibody is un-conjugated
    Application
    • 23
    • 19
    • 14
    • 4
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Purification
    Affinity chromatography purified via peptide column
    Immunogen
    Rabbit polyclonal TSPY1S antibody was raised against a 13 amino acid peptide near the carboxy terminus of human TSPY1S.
    Isotype
    IgG
    Top Product
    Discover our top product TSPY1 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    PBS containing 0.02 % Sodium Azide as preservative
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    -20 °C
    Storage Comment
    Store the antibody (in aliquots) at -20 °C.
  • Target
    TSPY1 (Testis Specific Protein, Y-Linked 1 (TSPY1))
    Alternative Name
    TSPY1 / TSPY (TSPY1 Products)
    Synonyms
    CT78 antibody, DYS14 antibody, TSPY antibody, pJA923 antibody, Tspy antibody, TSPY-M1 antibody, TSPY1 antibody, testis specific protein, Y-linked 1 antibody, TSPY1 antibody, Tspy1 antibody, TSPY antibody
    Background
    Testis-specific protein on Y chromosome (TSPY1) is an ampliconic gene on the Y chromosome that has been associated with gonadoblastoma. Recent experiments have shown that in androgen-dependent testicular germ-cell tumors, TSPY1 can repress the androgen-bound androgen receptor (AR), a member of the nuclear steroid hormone receptor family that acts as a ligand-inducible transcription factor, suggesting that TSPY1 is a repressor of cell proliferation in germ-cell tumors and potentially in normal gonadal cells during early development. Two distinct isoforms of TSPY1, TSPY1L and TSPY1S, are known to exist.Synonyms: CT78, Cancer/testis antigen 78, Testis-specific Y-encoded protein 1
    Molecular Weight
    32 kDa
    Gene ID
    7258
    NCBI Accession
    NP_001184171
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