TSPY1 antibody (C-Term, Isoform 2)

Catalog No. ABIN1450021

This Rabbit Polyclonal antibody specifically detects TSPY1 in WB and EIA. It exhibits reactivity toward Human and Mouse.

Quick Overview for TSPY1 antibody (C-Term, Isoform 2) (ABIN1450021)

Target: TSPY1 (Testis Specific Protein, Y-Linked 1 (TSPY1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TSPY1 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-TSPY1 Antibody

Binding Specificity: C-Term, Isoform 2

Purification: Affinity chromatography purified via peptide column

Immunogen: A 20 amino acid peptide near the carboxy terminus of human TSPY1L.

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for TSPY1

Target: TSPY1 (Testis Specific Protein, Y-Linked 1 (TSPY1))

Alternative Name: TSPY1 / TSPY

Background: Testis-specific protein on Y chromosome (TSPY1) is an ampliconic gene on the Y chromosome that has been associated with gonadoblastoma. Recent experiments have shown that in androgen-dependent testicular germ-cell tumors, TSPY1 can repress the androgen-bound androgen receptor (AR), a member of the nuclear steroid hormone receptor family that acts as a ligand-inducible transcription factor, suggesting that TSPY1 is a repressor of cell proliferation in germ-cell tumors and potentially in normal gonadal cells during early development. Two distinct isoforms of TSPY1, TSPY1L and TSPY1S, are known to exist.Synonyms: CT78, Cancer/testis antigen 78, Testis-specific Y-encoded protein 1

Molecular Weight: 34 kDa

Gene ID: 7258

NCBI Accession: NP_003299