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SHROOM3 antibody (Middle Region)

SHROOM3 Reactivity: Human WB, EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN1450022
  • Target See all SHROOM3 Antibodies
    SHROOM3 (Shroom Family Member 3 (SHROOM3))
    Binding Specificity
    • 5
    • 1
    • 1
    Middle Region
    Reactivity
    Human
    Host
    • 6
    • 1
    Rabbit
    Clonality
    • 7
    Polyclonal
    Conjugate
    • 3
    • 2
    • 1
    • 1
    This SHROOM3 antibody is un-conjugated
    Application
    • 5
    • 2
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Purification
    Affinity chromatography purified via peptide column
    Immunogen
    Rabbit polyclonal SHROOM3 antibody was raised against an 18 amino acid peptide near the center of Human SHROOM3
    Isotype
    IgG
    Top Product
    Discover our top product SHROOM3 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    PBS containing 0.02 % Sodium Azide as preservative
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    SHROOM3 (Shroom Family Member 3 (SHROOM3))
    Alternative Name
    SHROOM3 (SHROOM3 Products)
    Synonyms
    APXL3 antibody, SHRM antibody, ShrmL antibody, AL022960 antibody, D5Ertd287e antibody, Shrm antibody, Shrm3 antibody, RGD1310470 antibody, apxl3 antibody, shrm antibody, shroom family member 3 antibody, shroom family member 3 L homeolog antibody, SHROOM3 antibody, shroom3 antibody, Shroom3 antibody, shroom3.L antibody
    Background
    SHROOM family members play diverse roles in the development of the nervous system and other tissues. SHROOM3 is an actin-binding protein is a regulator of the microtubule cytoskeleton during epithelial morphogenesis and is sufficient and necessary to induce a redistribution of the microtubule regulator gamma-tubulin. It is necessary for both apiscobasal cell elongation and apical constriction in the neural epithelium (2,3) SHROOM3 has also been shown to be essential for cell shape changes and morphogenesis in the developing vertebrate gut, with its transcription relying on the Pitx1 transcription factor.Synonyms: APXL3, F-actin-binding, SHRM, SHROOM family member 3, ShrmL
    Molecular Weight
    220 kDa
    Gene ID
    57619
    NCBI Accession
    NP_065910
    Pathways
    Tube Formation, Asymmetric Protein Localization
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