UHRF1BP1 antibody (Middle Region)

Catalog No. ABIN1450049

The Rabbit Polyclonal anti-UHRF1BP1 antibody has been validated for WB, IF, IHC (p) and EIA. It is suitable to detect UHRF1BP1 in samples from Human and Mouse.

Quick Overview for UHRF1BP1 antibody (Middle Region) (ABIN1450049)

Target: UHRF1BP1 (UHRF1 Binding Protein 1 (UHRF1BP1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UHRF1BP1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Product Details anti-UHRF1BP1 Antibody

Binding Specificity: Middle Region

Cross-Reactivity (Details): Species reactivity (tested):Human, Mouse.

Purification: Affinity chromatography purified via peptide column

Immunogen: 17 amino acid synthetic peptide near the center of Human UHRF1BP1

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for UHRF1BP1

Target: UHRF1BP1 (UHRF1 Binding Protein 1 (UHRF1BP1))

Alternative Name: UHRF1BP1

Background: The Ubiquitin-like containing PHD and RING finger domains 1-binding protein 1 (UHRF1BP1), also known as ICBP90, is a transcription and cell cycle regulator. It specifically binds to the histone H3 N-terminal tail when methylated on K9 by two functional domains, a PHD finger that defines the binding specificity and an SRA (SET- and RING-associated) domain that promotes binding activity. UHRF1BP1 is required for proper heterochromatin formation in mammalian cells. Furthermore, UHRF1BP1 is thought to be a pivotal target for the ERK1/2 signaling pathway to control the proliferation of Jurkat T cells.Synonyms: ICBP90-binding protein 1, UHRF1 binding protein 1, Ubiquitin-like containing PHD and RING finger domains 1-binding protein 1

Gene ID: 54887

NCBI Accession: NP_060224