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Transglutaminase 5 (TGM5) (C-Term) antibody

Details for Product No. ABIN1450065
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Antigen
Synonyms TGASE5, TGASEX, TGMX, TGX, 2310007C07Rik, TGx, TGM5
Epitope
C-Term
(16), (7), (2), (1)
Reactivity
Human, Mouse (Murine), Rat (Rattus)
(31), (6), (5), (1), (1)
Host
Rabbit
(31), (1)
Clonality
Polyclonal
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1)
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (IF), ELISA, Western Blotting (WB)
(32), (23), (9), (3), (2)
Pubmed 5 references available
Quantity 0.1 mg
Shipping to United States (Change)
Availability Will be delivered in 6 to 8 Business Days
Catalog No. ABIN1450065
401.50 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen 19 amino acid synthetic peptide near the carboxy terminus of Human TGM5
Isotype IgG
Specificity This TGM5 antibody is predicted not to cross-react with other TGase protein family members. Multiple isoforms of TGM5 are known to exist.
Purification Affinity chromatography purified via peptide column
Alternative Name Transglutaminase-5 (TGM5)
Background Transglutaminases (TGM) are a family of structurally and functionally related Ca2+-dependent enzymes (TGases) that stabilize protein assemblies through the formation of gamma-glutamyl-epsilon lysine crosslinks. TGases influence numerous biological processes, including blood coagulation, cell differentiation, fertilization and apoptosis. TGM5 belongs to the transglutaminase superfamily and catalyzes the cross-linking of proteins between glutamine and lysine residues, often resulting in stabilization of protein assemblies. TGM5 is also expressed in the human hair follicle. Defects in TGM5 are associated with acral peeling skin syndrome.
Alternate names: Protein-glutamine gamma-glutamyltransferase 5, TGMX, TGX, TGase 5, TGase X, Transglutaminase X
Gene ID 9333
NCBI Accession NP_963925
Restrictions For Research Use only
Format Liquid
Concentration 1.0 mg/mL
Buffer PBS containing 0.02% Sodium Azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Expiry Date 12 months
Background publications Ueki, Takagi, Saito: "Dual functions of transglutaminase in novel cell adhesion." in: Journal of cell science, Vol. 109 ( Pt 11), pp. 2727-35, 1997 (PubMed).

Candi, Oddi, Terrinoni et al.: "Transglutaminase 5 cross-links loricrin, involucrin, and small proline-rich proteins in vitro." in: The Journal of biological chemistry, Vol. 276, Issue 37, pp. 35014-23, 2001 (PubMed).

Thibaut, Candi, Pietroni et al.: "Transglutaminase 5 expression in human hair follicle." in: The Journal of investigative dermatology, Vol. 125, Issue 3, pp. 581-5, 2005 (PubMed).

Cassidy, van Steensel, Steijlen et al.: "A homozygous missense mutation in TGM5 abolishes epidermal transglutaminase 5 activity and causes acral peeling skin syndrome." in: American journal of human genetics, Vol. 77, Issue 6, pp. 909-17, 2005 (PubMed).

Dewaele, Rasschaert, Wildemauwe et al.: "Polyphasic characterization of Salmonella Enteritidis isolates on persistently contaminated layer farms during the implementation of a national control program with obligatory vaccination: a longitudinal study." in: Poultry science, Vol. 91, Issue 11, pp. 2727-35, 2012 (PubMed).

Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN1450065
401.50 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
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