Transglutaminase 7 antibody (Middle Region)
Quick Overview for Transglutaminase 7 antibody (Middle Region) (ABIN1450066)
Target
See all Transglutaminase 7 (TGM7) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- Middle Region
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Purification
- Affinity chromatography purified via peptide column
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Immunogen
- 13 amino acid synthetic peptide near the center of Human TGM7
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Isotype
- IgG
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- PBS containing 0.02 % Sodium Azide as preservative
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Preservative
- Sodium azide
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Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freezing and thawing.
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Storage
- 4 °C/-20 °C
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Storage Comment
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Transglutaminase 7 (TGM7)
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Alternative Name
- Transglutaminase-7 (TGM7)
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Background
- Transglutaminases (TGM) are a family of structurally and functionally related Ca2+-dependent enzymes (TGases) that stabilize protein assemblies through the formation of gamma-glutamyl-epsilon lysine crosslinks. TGases influence numerous biological processes, including blood coagulation, cell differentiation, fertilization and apoptosis. TGM7 belongs to the transglutaminase superfamily and is also thought to catalyze the cross-linking of proteins, often resulting in stabilization of protein assemblies. Little is known of the role of TGM7, but defects in the highly related protein TGM5 are associated with acral peeling skin syndrome.Synonyms: Protein-glutamine gamma-glutamyltransferase Z, TGZ, TGase Z
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Gene ID
- 116179
Target
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