HILPDA antibody (C-Term)
Quick Overview for HILPDA antibody (C-Term) (ABIN1450090)
Target
See all HILPDA AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- C-Term
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Purification
- Affinity chromatography purified via peptide column
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Immunogen
- HIG2 antibody was raised against a 16 amino acid synthetic peptide near the carboxy terminus of human HIG2.
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Isotype
- IgG
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- PBS containing 0.02 % sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freezing and thawing.
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Storage
- -20 °C
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Storage Comment
- Store the antibody (in aliquots) at -20 °C.
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- HILPDA (Hypoxia Inducible Lipid Droplet-Associated (HILPDA))
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Alternative Name
- HIG2
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Background
- HIG1 and HIG2 (Hypoxia-inducible gene 1 and 2, respectively) are known to be induced by hypoxic conditions. HIG2 is induced by hypoxia and by glucose deprivation in cultured cells. In addition, tumor xenografts derived from human cervical cancer cells display increased expression of HIG1 and HIG2 when they are deprived of oxygen. Unlike HIG2, which is ubiquitously expressed and might be an activator and target of the canonical Wnt pathway, the function and the mechanisms underlying its regulation of HIG1 still remained unknown. The putative link between hypoxia and an oncogenic signaling pathway might play an important role in tumorigenesis.Synonyms: HILPDA, Hypoxia-inducible gene 2 protein
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Gene ID
- 29923
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NCBI Accession
- NP_001092256
Target
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