TCEB3B antibody (AA 101-150)

Catalog No. ABIN1534441

The Rabbit Polyclonal anti-TCEB3B antibody is suitable to detect TCEB3B in samples from Human, Mouse and Rat. It has been validated for ELISA and IF.

Quick Overview for TCEB3B antibody (AA 101-150) (ABIN1534441)

Target: TCEB3B (Transcription Elongation Factor B Polypeptide 3B (Elongin A2) (TCEB3B))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TCEB3B antibody is un-conjugated

Application: ELISA, Immunofluorescence (IF)

Product Details anti-TCEB3B Antibody

Binding Specificity: AA 101-150

Purpose: Elongin A2/3 Antibody

Specificity: Elongin A2/3 Polyclonal Antibody detects endogenous levels of Elongin A2/3 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human ELOA2. AA range:101-150

Isotype: IgG

Application Details

Application Notes: IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for TCEB3B

Target: TCEB3B (Transcription Elongation Factor B Polypeptide 3B (Elongin A2) (TCEB3B))

Alternative Name: ELOA2

Background:

Synonyms: TCEB3B, TCEB3L, RNA polymerase II transcription factor SIII subunit A2, Elongin-A2, EloA2, Transcription elongation factor B polypeptide 3B, TCEB3C, TCEB3L2, RNA polymerase II transcription factor SIII subunit A3, Elongin-A3, EloA3, Transcr

Background: This gene encodes the transcriptionally active subunit of the SIII (or elongin) transcription elongation factor complex, which also includes two regulatory subunits, elongins B and C. This complex acts to increase the rate of RNA chain elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites along the DNA template. Whereas a related protein with similar function, elongin A, is ubiquitously expressed, the encoded protein is specifically expressed in the testis, suggesting it may have a role in spermatogenesis. [provided by RefSeq, Jul 2008],

Gene Name: TCEB3B/TCEB3C

Protein Name: RNA polymerase II transcription factor SIII subunit A2/3

Molecular Weight: 83 kDa

Gene ID: 51224, 162699

OMIM: 609522

UniProt: Q8IYF1